Disclosure of interest
The authors have not supplied their declaration of competing interest.
Published online by Cambridge University Press: 23 March 2020
Cognitive impairment in patients with depressive disorder is a subject of intensive research.
This study deals with the cognitive impairment in patients with severe depressive episode with psychotic symptoms and patients with major depressive disorder during the acute state of illness.
The aim was to define domains and the level of cognitive impairment in both groups of patients.
The next aim was to compare profiles of cognitive impairment in both groups of patients.
The last aim was to find out a relationship between cognitive performance and severity of depressive episode during the acute state of illness.
We have used neuropsychological test battery (Auditory–Verbal Learning Test, Rey-Osterrieth Complex Figure Test, Logical Memory, Digit span test, Trail making test, Verbal Fluency Test, Block Design and Benton Visual Retention Test) for the evaluation of the cognitive functions in patients with severe depressive episode with psychotic symptoms (n = 5) and patients with major depressive disorder (n = 8).
We found cognitive impairment in all examined domains in both groups of patients.
More profound cognitive impairment was found in patients with severe depressive episode with psychotic symptoms, particularly in visual memory, visuo-constructive abilities, speed of cognitive processing and executive functions. We found no correlation between cognitive performance and severity of depressive episodes.
Our findings suggest a strong correlation between psychotic symptoms in depression and cognitive performance.
The authors have not supplied their declaration of competing interest.
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