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The treatment of anxiety disorders: a legacy of William Sargant*

Published online by Cambridge University Press:  16 April 2020

MG Gelder
MG Gelder*
Affiliation:
University Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, United Kingdom
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Summary

In 1962 William Sargant and his colleagues described the therapeutic value of phenelzine, a monoamine oxidase inhibitor (MAOI), in chronic anxiety disorders and in the same year Klein and Fink reported the treatment of similar conditions with imipramine, a tricyclic antidepressant. Subsequent research has confirmed these findings and demonstrated the range of similar drugs that are effective in anxiety disorders. At the time of these original observations about the drug treatment of anxiety, there were no psychological treatments of proven value but in the intervening years much progress has been made in developing behavioural and cognitive procedures. The progress in determining the mode of action of these pharmacological and psychological treatments is reviewed and the implications of the findings are considered in relation to research into the causes of the anxiety disorders and to the treatment of patients.

Keywords

anxiety disorderpharmacotherapycognitive behaviour therapy
Type
Original article
Information
European Psychiatry , Volume 12 , Issue 8 , 1997 , pp. 381 - 386
Copyright
Copyright © European Psychiatric Association 1997

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