Hostname: page-component-cd9895bd7-gbm5v Total loading time: 0 Render date: 2024-12-18T17:06:26.927Z Has data issue: false hasContentIssue false
  • English
  • Français

Virus de la enfermedad de Borna y psiquiatría

Published online by Cambridge University Press:  12 May 2020

O. Taieb ,
J. M. Baleyte ,
P. Mazet  and
A. M. Fillet
O. Taieb
Affiliation:
Departamento de Virología, CERVI, 47-83 Boulevard de I'Hôpital, 75013París, Francia Departamento de Psiquiatría del Niño y del Adolescente, Grupo Hospitalario Pitié-Salpêtrière, 47-83 Boulevard de I'Hôpital, 75013París, Francia
J. M. Baleyte
Affiliation:
Departamento de Psiquiatría del Niño y del Adolescente, Grupo Hospitalario Pitié-Salpêtrière, 47-83 Boulevard de I'Hôpital, 75013París, Francia
P. Mazet
Affiliation:
Departamento de Psiquiatría del Niño y del Adolescente, Grupo Hospitalario Pitié-Salpêtrière, 47-83 Boulevard de I'Hôpital, 75013París, Francia
A. M. Fillet
Affiliation:
Departamento de Virología, CERVI, 47-83 Boulevard de I'Hôpital, 75013París, Francia
Get access

Resumen

El virus de la enfermedad de Borna (VEB), un virus neurotrópico no citolítico con RNA “antisense” encapsulado no segmentado con una amplia distribución geográfica, infecta a varias especies de animales vertebrados y causa una enfermedad del sistema nervioso central (SNC) con mediación inmune y diversas manifestaciones, dependiendo tanto del huésped como de factores víricos. En las infecciones animales, el VEB puede persistir en el SNC e inducir alteraciones en las funciones de las células cerebrales, anomalías neuroevolutivas y perturbaciones del comportamiento. Algunos estudios serológicos y moleculares han propuesto una asociación entre el VEB y los trastornos psiquiátricos (esencialmente, la esquizofrenia y los trastornos afectivos), pero se requieren más investigaciones para establecer la posible contribución de este virus a la patogenésis de estos trastornos.

Keywords

autismotrastorno bipolarvirus de la enfermedad de Bornahipótesis neuroevolutivaesquizofrenia
Type
Revisión
Information
European Psychiatry (Ed. Española) , Volume 8 , Issue 4 , May 2001 , pp. 215 - 223
Copyright
Copyright © European Psychiatric Association 2001

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bibliografía

Bautista, JR, Schwartz, GJ, de, la Torre JC, Moran, TH, Carbone, KM, Early and persistent abnormalities in rats with neonatally acquired Borna disease virus infection. Brain Res Bull 1994; 34: 31–40.CrossRefGoogle ScholarPubMed
Bautista, JR, Rubio, SA, Moran, TH, Schwartz, GJ, Carbone, KM. Developmental injury to the cerebellum following perinatal Borna disease virus infection. Dev Brain Res 1995; 90: 45–53.CrossRefGoogle ScholarPubMed
Bechter, K, Herzog, S, Behr, W, Schuttler, R. Investigations of cerebrospinal fluid in Borna disease virus seropositive psychiatric patients. Eur Psychiatry 1995; 10: 250–8.CrossRefGoogle ScholarPubMed
Bode, L, Ferzt, R, Czech, G. Borna disease virus infection and affective disorders in man. Arch Virol 1993; 7 Supplu: 159–67.CrossRefGoogle ScholarPubMed
Bode, L, Zimmermann, W, Ferzt, R, Steinbach, F, Ludwig, H. Borna disease virus genome transcribed and expressed in psychiatric patients. Nat Med 1995; 1: 232–6.CrossRefGoogle ScholarPubMed
Bode, L, Durrwald, R, Rantam, FA, Ferzt, R, Ludwig, H. First isolates of infectious human Borna disease virus from patients with mood disorders. Mol Psychiatry 1996; 1: 200–12.Google ScholarPubMed
Bode, L, Dietrich, DE, Stoyloff, R, Emrich, HM, Ludwig, H. Amantadine and human Borna disease virus in vitro and in vivo in an infected patient with bipolar depression. Lancet 1997; 349: 178–9.CrossRefGoogle Scholar
Bode, L, Ludwig, H. Clinical similarities and close genetic relationship of human and animal Borna disease virus. Arch Virol 1997; 13 Suppl: 167–82.Google ScholarPubMed
Briese, T, Schneemann, A, Lewis, AJ, Park, YS, Kim, S, Ludwig, H, et al. Genomic organization of Borna disease virus. Proc Natl Acad Se USA 1994; 91: 4362–6.CrossRefGoogle ScholarPubMed
Briese, T, Lipkin, Wl, de, la Torre JC. Molecular biology of Borna disease virus. In: Koprowski, H, Lipkin, Wl, Eds. Borna discase.Berlin: Springer Verlag KG; 1995. p. 1–16.Google Scholar
Chen, CH, Chiu, YL, Wei, FC, Koong, FJ, Liu, HC, Shaw, CKI et al. High seroprevalence of Borna virus infection in schizophrenic patients, family members and mental health workers in Taiwan. Mol Psychiatry 1999; 4: 33–8.CrossRefGoogle Scholar
Cubitt, B, Oldstone, C, de, la Torre JC. Sequence and genomic organization of Borna disease virus. J Virol 1994; 68: 1382–96.CrossRefGoogle ScholarPubMed
Cubitt, B, de, la Torre JC. Amantadine does not have antiviral activiry against Borna disease virus. Arch Virol 1997; 142: 2035–42.CrossRefGoogle ScholarPubMed
Czygan, M, Hallensleben, W, Hofer, M, Pollak, S, Sauder, C, Bilzer, T, et al. Borna disease virus in human brains with a rare form of hippocampal degeneration but not in brains of patients with common neuropsychiatric disorders. J Infect Dis 1999; 180: 1695–9.CrossRefGoogle Scholar
de, la Torre JC. Molecular biology of Borna disease virus: prototype of a new group of animal viruses. J Virol 1994; 68: 7669–75.Google Scholar
de, la Torre JC, Bode, L, Durrwald, R, Cubitt, B, Ludwig, H. Sequence characterization of human Borna disease virus. Vims Res 1996; 44: 33–44.Google Scholar
de, la Torre JC, Gonzalez-Dunia, D, Cubitt, B, Mallory, M, Mueller-Lantzsch, N, Grasser, FA, et al. Detection of Borna disease virus antigen and RNA in human autopsy brain samples from neuropsychiatric patients. Virology 1996; 223: 272–82.Google Scholar
Deuschle, M, Bode, L, Heuser, I, Schmider, I, Ludwig, H. Borna disease virus proteins in cerebrospinal fluid of patients with recurrent depression and multiple sclerosis. Lancet 1998; 352: 1828–9.CrossRefGoogle ScholarPubMed
Fu, ZF, Amsterdam, JD, Kao, M, Shankar, V, Koprowski, H, Dietzschold, B. Detection of Borna disease virus reactive anti-bodies from patients with affictive disorders by western immunoblot technique. J Affect Dis 1993; 27: 61–8.CrossRefGoogle Scholar
Gonzalez-Dunia, D, Sauder, C, de, la Torre JC. Borna disease virus and the brain. Brain Res Bull 1997; 44: 647–64.CrossRefGoogle ScholarPubMed
Gosztonyi, G, Ludwig, H. Borna disease - neuropathology and pathogenesis. In: Koprowski, H, Lipkin, VA, Eds. Borna disease. Berlin: Springer Verlag KG; 1995. p. 39-73-Google ScholarPubMed
Haga, S, Motoi, Y, lkeda, K. Borna disease virus and neuropsychiatric disorders. Lancet 1997; 350: 592–3.CrossRefGoogle ScholarPubMed
Hallensleben, W, Zocher, M, Stacheli, P. Borna disease virus is not sensitive to amantadine. Arch Virol 1997; 142: 2043–8.CrossRefGoogle Scholar
Hatalski, CG, Lewis, AJ, Lipkin, Wl. Borna disease. Emerging Infect Dis 1997; 3: 129–35.CrossRefGoogle ScholarPubMed
Hornig, M, Weissenbock, H, Horscroft, N, Lipkin, WI. An infection based model of neurodevelopmental damage. Proc Natl Acad Se USA 1999; 96: 12102–7.CrossRefGoogle ScholarPubMed
Igata, Yi R, Yamaguchi, K, Yoshiki, K, Takemoto, S, Yamasaki, H, Matsuoka, M, et al. Borna disease virus and the consumption of raw horse meat. Nat Med 1996; 2: 948–9.CrossRefGoogle Scholar
Iwahashi, K, Watanabe, M, Nakamura, K, Suwaki, H, Nakaya, T, Nakamura, Y, et al. Clinical investigation of the relationship between Borna disease infection and schizophrenia in 67 patients in Japan. Acta Psychiatr Scand 1997; 96: 412–5.CrossRefGoogle ScholarPubMed
Iwahashi, K, Watanabe, M, Nakamura, K, Suwaki, H, Nakaya, T, Nakamura, Y, et al. Positive and negative syndromes and Borna disease infection in schizophrenia. Neuropsychobiol 1998; 37: 59–64.CrossRefGoogle Scholar
Iwata, Y, Takahashi, K, Peng, X, Fukuda, K, Ohno, K, Ogawa, T, et al. Detection and sequence analysis of Borna disease virus p24 RNA from peripheral blood mononu clear cells of patients with mood disorders or schizophrenia and of blood donors. J Virol 1998; 72: 10044–9.CrossRefGoogle ScholarPubMed
Jordan, I, Briese, T, Averett, DR, Lipkin, WI. Inhibition of Borna disease virus replication by ribavirin. J Virol 1999; 73: 7903–6.CrossRefGoogle ScholarPubMed
Kim, YK, Kim, SH, Choi, SH, Ko, YH, Kim, L, Lee, MS, et al. Failure to demonstrate Borna disease virus genome in peripheral blood mononuclear cells from psychiatric patients in Korea. I Neurovirol 1999; 5: 196–9.CrossRefGoogle ScholarPubMed
Kishi, M, Nakaya, T, Nakamura, Y, Zhong, Q, lkeda, K, Senjo, M, et al. Demonstration of human Borna disease virus RNA in human peripheral blood mononuclear cells. FEBS Lett 1995; 363: 293–7.CrossRefGoogle Scholar
Kishi, M, Nakaya, T, Nakamura, Y, Kakinuma, M, Takahashi, TA, Sekiguchi, S, et al. Prevalence of Borna disease virus RNA in peripheral blood mononuclear cells from blood donors. Med Microbiol Immunol 1995; 184: 135–8.CrossRefGoogle ScholarPubMed
Kubo, K, Fujiyoshi, T, Yokoyama, MM, Kamel, K, Wcht, JA, Kitze, B, et al. Lack of association of Borna disease virus and human T-cell leukemia virus type 1 infections with psychiatric disorders among Japanese patients. Clin Diagn Lab Immunol 1997; 4: 189–94.CrossRefGoogle ScholarPubMed
Lieb, K, Hufert, FT, Bechter, K, Bauer, J, Kornhuber, J. Depression, Borna disease and amantadine. Lancet 1997; 349: 958.CrossRefGoogle ScholarPubMed
Lieb, K, Haltensleben, W, Czygan, M, Stitz, L, Staeheli, P. No Borna disease virus-specific RNA detected in blood from psychiatric patients in different regions of Germany. Lancet 1997; 350: 1002.CrossRefGoogle ScholarPubMed
Mizutani, T, Inagaki, H, Araki, K, Kariwa, H, Arikawa, J, Takashima, I. Inhibition of Borna disease by ribavirin in persistently infected cells. Arch Virol 1998; 143: 2039–44.CrossRefGoogle ScholarPubMed
Nowotny, N, Windhaber, J. Borna disease virus and neuropsychiatric disorders. Lancet 1997; 350: 593.CrossRefGoogle Scholar
Planz, O, Rentzsch, C, Batra, A, Rziha, HJ, Stitz, L. Persistence of Borna disease virus-specific nucleic acid in blood of psychiatric patient. Lancet 1998; 352: 623.CrossRefGoogle ScholarPubMed
Planz, O, Rentzch, C, Batra, Al, Winkler, T, Buttner, M. Pathogenesis of Borna disease virus: granulocyte fractions of psychiatric patients harbor infectious virus in the absence of antiviral antibodies. J Virol 1999; 73: 625 1–6.CrossRefGoogle ScholarPubMed
Pletnikov, MV, Rubin, SA, Vasudevan, K, Moran, TH, Carbone, KM. Developmental brain injury associated with abnormal play behavior in neonatally Borna disease virus-infected Lewis rats: a model of autism. Behav Brain Res 1999; 100: 43–50.CrossRefGoogle Scholar
Pletnikov, MV, Rubin, SA, Schwartz, GJ, Moran, TH, Sobotka, Ti, Carbone, KM, et al. Persistent neonatal Borna disease virus infection of the brain causes chronic emotional abnormalities in rats. Physiol Behav 1999; 66: 823–31.CrossRefGoogle Scholar
Richt, JA, Alexander, RC, Herzog, S, Hooper, DC, Kean, R, Spitsin, S, et al. Faiture to detect Borna disease virus infection in peripheral blood leucocytes from humans with psychiatric disorders. J Neurovirol 1997; 3: 174–8.CrossRefGoogle Scholar
Richt, JA, Pfeuffer, I, Christ, M, Frese, K, Bechter, K, Herzog, S. Borna disease virus infection in animals and humans. Emerg Infect Dis 1997; 3: 343–52.CrossRefGoogle ScholarPubMed
Rott, R, Becht, H. Natural and experimental Borna disease in animals. In Koprowski, H, , Lipkin Vn, Eds. Borna disease. Berlin: Springer Verlag KG; 1995. p. 17-30.Google ScholarPubMed
Rubin, SA, Sierra-Honigmann, AM, Lederman, HM, Waltrip, RW, Eiden, JJ, Carbone, KM. Hematologic consequences of Borna disease virus infection of rat bone marrow and thymus stromal cells. Blood 1995; 85: 2762–9.Google ScholarPubMed
Rubin, SA, Sylves, P, Vogel, M, Pletnikov, M, Moran, TO, Schwartz, GJ, et al. Borna disease virus-induced hippocam-pal dentate gyrus damage is associated with spatial learning and memory deficits. Brain Res Bull 1998; 48: 22–30.Google Scholar
Rubin, SA, Bautista, JR, Moran, TO, Schwartz, GJ, Carbone, KM. Vital teratogenesis-. brain developmental damage associated with maturation state at time of infection. Dev Brain Res 1999; 112: 237–44.Google Scholar
Salvatore, M, Morzunov, S, Schwemmle, M, Lipkin, WI. Borna disease virus in brains of North American and European people with schizophrenia and bipolar disorder. Lancet 1997; 349: 1813–4.CrossRefGoogle ScholarPubMed
Sauder, C, Muller, A, Cubitt, B, Mayer, J, Steinmetz, J, Trabert, W, et al. Detection of Borna disease virus antibodies and BDV RNA in psychiatric patients: evidence for high sequence conservation of human blood-derived BDV RNA. J Virol 1996; 70: 7713–24.CrossRefGoogle ScholarPubMed
Sauder, C, de, la Torre JC. Sensitivity and reproducibiliy of RT-PCR to detect Borna disease virus RNA in blood: implications for BDV epidemiology. J Virol Methods 1998; 71: 229–45.CrossRefGoogle Scholar
Schwemmle, M, Jehle, C, Formella, S, Staeheli, P. Sequence similarities between human bornavirus isolates and laboratory strains question human origin. Lancet 1999; 354: 1973–4.CrossRefGoogle ScholarPubMed
Sierra-Honigmann, AM, Carbone, KM, Yolken, RH. Polymerase chain reaction search for vital nucleic acid sequences in schizophrenia. Br J Psychiatry 1995; 166: 55–60.CrossRefGoogle Scholar
Solbrig, MV, Fallon, JH, Lipkin, WI. Behavioral disturbances and pharmacology of Borna disease. In Koprowski, H, Lipkin, WI, Eds. Borna disease. Berlin: Springer Verlag KG; 1995. p. 93-101.Google ScholarPubMed
Solbrig, MV, Koob, GF, Fallon, JH, Reid, S, Lipkin, WI. Prefrontal cortex dysfunction in Borna disease virus-infected rats. Biol Psychiatry 1996; 4: 629–36.CrossRefGoogle Scholar
Solbrig, MV, Koob, GF, Joyce, JN, Lipkin, WI. A neural substrate of hyperactivity in Borna disease: changes in brain dopamine receptors. Virology 1996; 222: 332–8.CrossRefGoogle ScholarPubMed
Stitz, L, Dietzschold, B, Carbone, KM. Immunopathogenesis of Borna disease. In Koprowski, H, Lipkin, WI, Eds. Borna disease. Berlin: Springer Verlag KG; 1995. p. 75-91.Google ScholarPubMed
Stitz, L, Planz, O, Bilzer, T. Lack of antiviral effect of amantadine in Borna disease virus infection. Med Microbiol Immunol 1998; 186: 195–200.CrossRefGoogle ScholarPubMed
Waltrip, IIRW, Buchanan, RW, Summerfelt, A, Breier, A, Car-penter, WT, Bryant, NL, et al. Borna disease virus and schizophrenia. Psychiatry Res 1995; 56: 33–44.CrossRefGoogle Scholar
Waltrip, IIRW, Buchanan, RW, Carpenter, VU, Kirkpatrick, B, Summerfelt, A, Breier, A, et al. Borna disease virus antibodies and the deficit syndrome of schzophrenia. Schizophr Res 1997; 23: 253–7.CrossRefGoogle Scholar