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Fenotipos marginales en el autismo: una revisión de los estudios clínicos, bioquímicos y cognitivos

Published online by Cambridge University Press:  12 May 2020

V. Goussé ,
M.H. Plumet ,
N. Chabane ,
M.C. Mouren-Siméoni ,
N. Ferrandian  and
M. Leboyer
V. Goussé
Affiliation:
Consulta de autismo, Servicio de Psicopatología del Niño y del Adolescente, Hospital Robert Debré, Asistencia Pública-Hospitales de Paris, 75019París, Francia INSERM U 513, Hospital Albert Chenevier y Henri Mondor
M.H. Plumet
Affiliation:
Consulta de autismo, Servicio de Psicopatología del Niño y del Adolescente, Hospital Robert Debré, Asistencia Pública-Hospitales de Paris, 75019París, Francia
N. Chabane
Affiliation:
Consulta de autismo, Servicio de Psicopatología del Niño y del Adolescente, Hospital Robert Debré, Asistencia Pública-Hospitales de Paris, 75019París, Francia INSERM U 513, Hospital Albert Chenevier y Henri Mondor
M.C. Mouren-Siméoni
Affiliation:
Consulta de autismo, Servicio de Psicopatología del Niño y del Adolescente, Hospital Robert Debré, Asistencia Pública-Hospitales de Paris, 75019París, Francia
N. Ferrandian
Affiliation:
Asistencia Pública-Hospitales de Paris, 40, rue de Mesly, 94000Créteil, Francia
M. Leboyer
Affiliation:
Consulta de autismo, Servicio de Psicopatología del Niño y del Adolescente, Hospital Robert Debré, Asistencia Pública-Hospitales de Paris, 75019París, Francia INSERM U 513, Hospital Albert Chenevier y Henri Mondor Asistencia Pública-Hospitales de Paris, 40, rue de Mesly, 94000Créteil, Francia
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Resumen

El progreso en la identificación de los factores de vulnerabilidad genética en el autismo requiere la identificación correcta del fenotipo o fenotipos heredados. Esto se puede lograr no sólo por la descripción precisa del sujeto afectado, sino también por la identificación de los rasgos de vulnerabilidad en familiares no afectados de los probandos autistas. Esta revisión se centrará en esta última estrategia y principalmente en los rasgos clínicos, bioquímicos y cognitivos.

Keywords

autismogenética psiquiátricafenotiposevaluaciones cognitivasclínicas y bioquimicas
Type
Revision
Information
European Psychiatry (Ed. Española) , Volume 9 , Issue 7 , October 2002 , pp. 421 - 429
Copyright
Copyright © European Psychiatric Association 2002

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Footnotes

GousseV, PlumetM-H, ChabaneN, Mouren-SimeoniM-C, FerradianN, LeboyerM. Fenotipos marginales en el autismo: una revisión de los estudios clínicos, bioquímicos y cognitivos. Eur Psychiatry2002; 17: 120–8.

References

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