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The use of a radial haemolysis test for neuraminidase antibodies in the diagnosis of influenza A infection

Published online by Cambridge University Press:  19 October 2009

E. A. Grilli  and
A. J. Smith
E. A. Grilli
Affiliation:
Influenza Research Unit, Public Health Laboratory, St Luke's Hospital, Guildford, Surrey GU1 3NT
A. J. Smith
Affiliation:
Influenza Research Unit, Public Health Laboratory, St Luke's Hospital, Guildford, Surrey GU1 3NT
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Summary

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A radial haemolysis test designed to detect antibody specifically directed against the neuraminidase is described and compared with currently available techniques for the routine diagnosis of infection with influenza viruses.

Paired sera were available from two outbreaks of influenza A, one with the N1N1 subtype and the other with the H3N2 subtype. This technique confirmed diagnosis in 92% of cases diagnosed by other laboratory methods.

Type
Research Article
Information
Journal of Hygiene , Volume 91 , Issue 1 , August 1983 , pp. 147 - 156
Copyright
Copyright © Cambridge University Press 1983

References

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