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Characterization of human rotavirus strains causing gastroenteritis in Kenya

Published online by Cambridge University Press:  19 October 2009

Z. Gatheru ,
N. Kobayashi ,
N. Adachi ,
S. Chiba ,
J. Muli ,
P. Ogaja ,
J. Nyangao ,
E. Kiplagat  and
P. M. Tukei
Z. Gatheru
Affiliation:
Virus Research Centre, Kenya Medical Research Institute, P.O. Box 54S40, Nairobi, Kenya
N. Kobayashi*
Affiliation:
Department of Hygiene, Sapporo Medical College, S-l, W-17, Chuo-ku, Sapporo, Japan
N. Adachi
Affiliation:
Department of Pediatrics, Sapporo Medical College, S-l, W-16, Chuo-ku, Sapporo, Japan
S. Chiba
Affiliation:
Department of Pediatrics, Sapporo Medical College, S-l, W-16, Chuo-ku, Sapporo, Japan
J. Muli
Affiliation:
Virus Research Centre, Kenya Medical Research Institute, P.O. Box 54S40, Nairobi, Kenya
P. Ogaja
Affiliation:
Virus Research Centre, Kenya Medical Research Institute, P.O. Box 54S40, Nairobi, Kenya
J. Nyangao
Affiliation:
Virus Research Centre, Kenya Medical Research Institute, P.O. Box 54S40, Nairobi, Kenya
E. Kiplagat
Affiliation:
Virus Research Centre, Kenya Medical Research Institute, P.O. Box 54S40, Nairobi, Kenya
P. M. Tukei
Affiliation:
Virus Research Centre, Kenya Medical Research Institute, P.O. Box 54S40, Nairobi, Kenya
*
*Corresponding author.
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Summary

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Human rotavirus strains from Kenya, from children with gastroenteritis in an urban area (Nairobi) and three rural areas were characterized by antigenic and genomic analysis. While in all areas strains with subgroups II and G serotype 1 antigens were most common, two unusual strains were detected. One strain (NK59: subgroup II. G serotype 4) possessed an additional RNA band on polyacrylamide gel electrophoresis, the other (D202) which had antigenic specificity of subgroup II and G serotype 1 showed a ‘short’ RNA pattern. The latter strain was adapted to growth in cell culture.

Type
Research Article
Information
Epidemiology & Infection , Volume 110 , Issue 2 , April 1993 , pp. 419 - 423
Copyright
Copyright © Cambridge University Press 1993

References

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