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Antirabic immunity in guinea-pigs induced by high egg passage Flury virus. The influence of the route of administration on the resistance to cerebral and extraneural challenge

Published online by Cambridge University Press:  15 May 2009

C. Huygelen
C. Huygelen
Affiliation:
Veterinary Research Laboratory, Astrida, Ruanda-Urundi, Belgian Congo
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Immunization experiments in guinea-pigs with high egg passage Flury virus gave the following results:

1. Intracerebral inoculation of the vaccine protects against subsequent intracerebral or peripheral challenge with fixed virus.

2. Intramuscular administration results in the development of a good immunity status to peripheral challenge.

3. Intramuscular or intravenous inoculation of the vaccine fails to protect against intracerebral challenge.

Type
Research Article
Information
Journal of Hygiene , Volume 58 , Issue 2 , June 1960 , pp. 187 - 191
Copyright
Copyright © Cambridge University Press 1960

References

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