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The bases of western attitudes to consanguineous marriage

Published online by Cambridge University Press:  10 January 2003

A H Bittles
Affiliation:
Centre for Human Genetics, Edith Cowan University, Perth WA 6027, Australia.
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Abstract

There are frequent references to marriages between close biological relatives in the Bible, for example, the Patriarch Abraham and his wife Sarah (Genesis 20:12), and Amran and Jochebed, the parents of Aaron and Moses, who were related as nephew and aunt (Exodus 6:20). In both cases the parental couple would be expected to have inherited identical genes from a common ancestor(s) at 25% of all loci and so, on average, their offspring would have been homozygous at 12.5% of loci, equivalent to a coefficient of inbreeding (F) of 0.125.

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© 2003 Mac Keith Press

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