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Coping with having a depressed mother: The role of stress and coping in hypothalamic–pituitary–adrenal axis dysfunction in girls at familial risk for major depression

Published online by Cambridge University Press:  25 November 2014

Lara C. Foland-Ross ,
Katharina Kircanski  and
Ian H. Gotlib
Lara C. Foland-Ross*
Affiliation:
Stanford University
Katharina Kircanski
Affiliation:
Stanford University
Ian H. Gotlib
Affiliation:
Stanford University
*
Address correspondence and reprint requests to: Lara Foland-Ross, Stanford Mood and Anxiety Disorders Laboratory, Department of Psychology, Stanford University, Jordan Hall, Building 420, 450 Serra Mall, Stanford, CA 94305; E-mail: [email protected].
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Abstract

Having a depressed mother is one of the strongest predictors of depression in adolescence. We investigated whether the stress of having a mother with recurrent depression is associated with dysfunction in adolescents in the HPA axis and whether the tendency to use involuntary coping strategies in dealing with this stress is associated with exacerbation of dysfunction in this system. Sixty-four never-disordered daughters of mothers with recurrent depression (high risk) and 64 never-disordered daughters of never-disordered mothers (low risk) completed diurnal cortisol and stress assessments. High-risk girls secreted more diurnal cortisol than did low-risk girls. Whereas low-risk girls secreted higher levels of cortisol with increasing stress associated with having a depressed mother, no such relation was present in high-risk girls. Finally, in contrast to low-risk girls, girls at familial risk for depression who more frequently used involuntary versus voluntary coping exhibited the greatest elevations in diurnal cortisol. These findings indicate that a tendency to utilize involuntary, as opposed to voluntary, coping strategies in dealing with stress involving maternal depression exacerbates already high levels of cortisol in youth at risk for depression. Future research that examines whether interventions aimed at increasing the use of voluntary coping strategies normalizes HPA axis dysfunction is of interest.

Type
Regular Articles
Information
Development and Psychopathology , Volume 26 , Special Issue 4pt2: Multilevel Developmental Perspectives Toward Understanding Internalizing Psychopathology: Current Research and Future Directions , November 2014 , pp. 1401 - 1409
Copyright
Copyright © Cambridge University Press 2014 

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