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Genetics of Schizophrenia: Current Findings and Issues

Published online by Cambridge University Press:  07 November 2014

James L. Kennedy ,
Michele T. Pato ,
Amy Bauer ,
Celia Carvalho  and
Carlos N. Pato
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Abstract

The genetics of schizophrenia are characterized by a set of complex questions, with few answers forthcoming. However, molecular genetic approaches remain the most promising avenue to the understanding of etiologic mechanisms. Powerful discoveries may arise in the near future from candidate gene studies that are benefiting from the extensive neurobiology research in schizophrenia over the past decades. Furthermore, there are promising new divisions of the phenotype into more manageable subtypes that may make both candidate gene and genome scan studies more revealing. The following review discusses selected highlights of the epidemiology, molecular genetic strategies, candidate genes, and genome scan investigations in schizophrenia.

Type
Feature Articles
Information
CNS Spectrums , Volume 4 , Issue 5: Molecular Genetics: Part One , May 1999 , pp. 17 - 21
Copyright
Copyright © Cambridge University Press 1999

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