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Volume 6 - January 1996

Contents

Page 5 of 5

Brief Reports

  • Propafenone associated granulocytopenia in a newborn

  • Thomas Paul, Ingrid Luhmer, Alfred Reiter
  • Published online by Cambridge University Press:
    19 August 2008, pp. 348-349

  • Progressive granulocytopenia (neutrophil count <1000/ml) developed in a newborn during treatment with propafenone (200 mg/m2) for recurrent paroxysmal supraventricular tachycardia. The total white blood cell count, however, remained within normal limits. The neutrophil count increased gradually after propafenone had been stopped. The time course of treatment and the development of granulocytopenia make it very likely, but not certain, that propafenone was the responsible agent. Pediatricians, and especially pediatric cardiologists, should be aware of this rare adverse effect when they consider treatment with propafenone in children with cardiac arrhythmias. Analysis of the white cell blood count, including a differential count, is recommended in all children in order to assess the true incidence of this adverse effect.

Front cover (OFC, IFC) and matter

Brief Reports

Back cover (IBC, OBC) and matter

Letters to the Editor

  • To the Editor

  • Leon M. Gerlis
  • Published online by Cambridge University Press:
    19 August 2008, p. 102
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Letter to the Editor

  • Letter to the Editor

  • Richard J. Mullaly
  • Published online by Cambridge University Press:
    19 August 2008, p. 350
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Author Index

Letters to the Editor

  • To the Editor

  • Dieter Lang
  • Published online by Cambridge University Press:
    19 August 2008, p. 102
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Subject Index

Book Reviews

From the Founder

Book Reviews

Front cover (OFC, IFC) and matter

Back cover (IBC, OBC) and matter

Page 5 of 5