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Mechanical circulatory support in paediatric population

Part of: Surgery

Published online by Cambridge University Press:  11 January 2021

Naomi Melamed ,
Sashini Iddawela ,
Grace Olivia Jane Poole ,
Ayomikun Ajibade  and
Amer Harky Open the ORCID record for Amer Harky [Opens in a new window]
Naomi Melamed
Affiliation:
St George’s Medical School, University of London, London, UK
Sashini Iddawela
Affiliation:
Department of Respiratory Medicine, University Hospitals Birmingham, Birmingham, UK
Grace Olivia Jane Poole
Affiliation:
St George’s Medical School, University of London, London, UK
Ayomikun Ajibade
Affiliation:
Birmingham Medical School, University of Birmingham, Birmingham, UK
Amer Harky*
Affiliation:
Department of Cardiothoracic Surgery, Liverpool Heart and Chest Hospital, Liverpool, UK Department of Cardiac Surgery, Alder Hey Children’s Hospital, Liverpool, UK Department of Integrative Biology, Faculty of Life Sciences, University of Liverpool, Liverpool, UK Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart and Chest Hospital, Liverpool, UK
*
Author for correspondence: Dr A. Harky, MSc, MRCS, Department of Cardiac Surgery, Alder Hey Children Hospital, E Prescot Rd, Liverpool L14 5AB, UK. Tel: +44-151-228-4811. E-mail: [email protected]
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Abstract

Extra-corporeal membrane oxygenation is a life-saving modality to support the cardiac and/or pulmonary system as a form of life support in resuscitation, post-cardiotomy, as a bridge to cardiac transplantation and in respiratory failure. Its use in the paediatric and neonatal population has proven incredibly useful. However, extra-corporeal membrane oxygenation is also associated with a greater rate of mortality and complications, particularly in those with co-morbidities. As a result, interventions such as ventricular assist devices have been trialled in these patients. In this review, we provide a comprehensive analysis of the current literature on extra-corporeal membrane oxygenation for cardiac support in the paediatric and neonatal population. We evaluate its effectiveness in comparison to other forms of mechanical circulatory support and focus on areas for future development.

Keywords

ECMOpaediatricsneonatescardiac surgeryVADsMCS
Type
Review
Information
Cardiology in the Young , Volume 31 , Issue 1 , January 2021 , pp. 31 - 37
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Copyright
© The Author(s), 2021. Published by Cambridge University Press

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Footnotes

Naomi Melamed and Sashini Iddawela are both first authors on this review with a shared first co-authorship.

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