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Etoposide-related cardiotoxicity in a child with haemophagocytic lymphohistiocytosis

Published online by Cambridge University Press:  25 February 2010

Heather Escoto ,
Jeremy Ringewald  and
Ram Kalpatthi
Heather Escoto
Affiliation:
Division of Pediatric Hematology and Oncology, Medical University of South Carolina, Charleston, South Carolina, United States of America
Jeremy Ringewald
Affiliation:
Division of Cardiology, Medical University of South Carolina, Charleston, South Carolina, United States of America
Ram Kalpatthi*
Affiliation:
Division of Pediatric Hematology and Oncology, Medical University of South Carolina, Charleston, South Carolina, United States of America
*
Correspondence to: Ram Kalpatthi, MD, Division of Pediatric Hematology Oncology, Children’s Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108. Tel: 816-234-3265; Fax: 816-855-1700; E-mail: [email protected]
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Abstract

We report a male child with haemophagocytic lymphohistiocytosis who developed myocardial infarction after receiving etoposide. He recovered well with supportive measures and after discontinuation of etoposide. We discuss the possible mechanisms and differential diagnoses of myocardial infarction in our patient.

Keywords

Chemotherapymyocardial infarctionelectrocardiogram
Type
Brief Reports
Information
Cardiology in the Young , Volume 20 , Issue 1 , February 2010 , pp. 105 - 107
Copyright
Copyright © Cambridge University Press 2010

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