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Elucidation of digital clubbing may help in understanding the pathogenesis of pulmonary hypertension associated with congenital heart defects

Published online by Cambridge University Press:  19 August 2008

Manuel Martínez-Lavín
Affiliation:
Instituto Nacional de Cardiología “Ignacio Chávez”Juan Badiano 1, Tlalpan14080 México D.F., México
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Abstract

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Type
Editorials
Copyright
Copyright © Cambridge University Press 1994

References

Vázquez-Abad, D, Martínez-Lavín, M.Macrothrombocytes in the peripheral circulation of patients with cardiogenic hypertrophic osteoarthropathy. Clin Exp Rheumatol 1991; 9: 5962.Google ScholarPubMed
Martínez-Lavín, M, Piñeda, C.Digital clubbing. Lancet 1990; 2: 1444.[Letter]CrossRefGoogle Scholar
Matucci-Cerinic, M, Martmnez-Lavín, M, Rojo, F, Fonseca, C, Kahaleh, B. von Willebrand factor in hypertrophic osteoarthropathy. J Rheumatol 1992; 19: 765767.Google ScholarPubMed
Rabinovitch, M. Pulmonary hypertension. In: Moss, E (ed). Heart Disease in Children and Adolescents. Williams and Wilkins, Baltimore, 1989, pp 856886.Google Scholar
Heath, D, Edwards, E.The pathology of hypertensive vascular disease. Circulation 1958: 18, 533547.CrossRefGoogle Scholar
Rabinovitch, M, Bothwell, T, Hayakawa, B, Williams, W, Trusler, G, Rowe, R, Olley, P.Pulmonary endothelial abnormalities in patients with congenital heart defects and pulmonary hypertension. Lab Inv 1986; 55: 632653.Google ScholarPubMed
Sixma, J, de Groot, P.von Willebrand factor and the blood vessel wall. Mayo Clin Proc 1991; 66: 628633.CrossRefGoogle ScholarPubMed
Meyer, D, Pietu, G, Fressinaud, E, Girma, J.von Willebrand factor; structure and function. Mayo Clin Proc 1991; 66: 516523.CrossRefGoogle ScholarPubMed
Rabinovitch, M, Andrew, M, Thom, H, Truler, G, Williams, W, Rowe, R, Olley, P. Abnormal endothelial factor VIII associated with pulmonary hypertension and congenital heart defects. Circulation 1987; 76: 10431052.CrossRefGoogle ScholarPubMed
Gill, J, Wilson, A, Endress-Brooks, J, Montgomery, R.Loss of largest von Willebrand factor multimers from plasma ofpatients with congenital heart defects. Blood 1986; 67: 758761.CrossRefGoogle Scholar
Vázquez-Abad, D, Martínez-Lavín, M.Digital clubbing; a merical assessment of the deformity. J Rheumatol 1989; 16: 518520.Google Scholar
Martínez-Lavín, M, Bobadilla, M, Casanova, JM, Attié, F, Martínez, M.Hypertrophic osteoarthropathy in cyanotic congenital heart diseases; its prevalence and relationship with bypass of the lung. Arthritis Rheum 1982; 28: 461475.Google Scholar
Martínez-Lavín, M.Digital clubbing and hypertrophic osteoarthropathy; a unifying hypothesis. J Rheumatol 1987 14: 68.Google ScholarPubMed
Dickinson, CJ, Martin, JF.Megakasyocytes and platelet clumps as the cause of finger clubbing. Lancet 1987; 2: 14341435.CrossRefGoogle ScholarPubMed
Chirstman, B, McPherson, C, Newman, J, King, G, Bernard, G, Groves, B, Loyd, J.An imbalance between the excretion of thromboxane and protacyclin metabolites in pulmonary hypertension. N Engl J Med 1992; 327: 7075.CrossRefGoogle Scholar