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Impact of the Cognitive Status on the Memory Complaints in MS Patients

Published online by Cambridge University Press:  18 February 2016

M. Demers ,
I. Rouleau ,
P. Scherze ,
J. Ouellet ,
C. Jobin  and
P. Duquette
M. Demers
Affiliation:
Département de psychologie, and Institut des sciences cognitives, Université du Québec à Montréa, UQAM, Montréal, Quebec, Canada
I. Rouleau*
Affiliation:
Département de psychologie, and Institut des sciences cognitives, Université du Québec à Montréa, UQAM, Montréal, Quebec, Canada MS Clinic, Centre Hospitalier de l'Université de Montréal, Montréal, Quebec, Canada
P. Scherze
Affiliation:
Département de psychologie, and Institut des sciences cognitives, Université du Québec à Montréa, UQAM, Montréal, Quebec, Canada
J. Ouellet
Affiliation:
Département de psychologie, and Institut des sciences cognitives, Université du Québec à Montréa, UQAM, Montréal, Quebec, Canada
C. Jobin
Affiliation:
Institut de Réadaptation Gingras-Lindsay de Montréal, Hôpital du Sacré-Coeur, Montréal, Quebec, Canada
P. Duquette*
Affiliation:
MS Clinic, Centre Hospitalier de l'Université de Montréal, Montréal, Quebec, Canada
*
Département de psychologie, Université du Québec à Montré, CP 8888, Succ. Centre-ville, Montréal, QC, H3C 3P8, Canada
Département de psychologie, Université du Québec à Montré, CP 8888, Succ. Centre-ville, Montréal, QC, H3C 3P8, Canada
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Abstract:

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Objective:

Despite the evidence of cognitive deficits in Multiple Sclerosis (MS) patients, evaluation of their cognitive integrity is often limited to the use of clinical interviews and questionnaires. However, the consensus in the literature is that these patients under- or overestimate their deficits and repercussions. The objective of this study was to clarify why some patients overestimate while others underestimate their memory deficits.

Method:

Fifty-four participants (30 MS, 24 controls) completed the Prospective and Retrospective Memory Questionnaire (PRMQ) and were tested on a battery of neuropsychological tests. Based on the test results, MS patients were categorized as having either mild or moderate/severe cognitive deficits.

Results:

The moderate/severe MS group differed from the two other groups on the Rey Auditory Verbal Learning Test (RAVLT) but did not differ from the control group on the PRMQ. Conversely, the mild MS group did not differ from the control group on the RAVLT but did report significantly more problems than this group on the PRMQ. There was no difference between the two clinical groups on the Depression Index (Beck) but there was a significant correlation (r=.409) between the depression scores and the overestimation of prospective memory problems (PRMQ).

Conclusion:

The results explain the contradiction in the literature. It is the mild group who overestimates, maybe because they are overly concerned by their deficits, whereas the cognitive impairments of the moderate/severe group lead them to underestimate and may make their self-assessment unreliable. Formal testing or information from a significant other would be advisable.

Type
Original Article
Information
Canadian Journal of Neurological Sciences , Volume 38 , Issue 5 , September 2011 , pp. 728 - 733
Copyright
Copyright © Canadian Neurological Sciences Federation 2011

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