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Disorders of Neuronal Migration

Published online by Cambridge University Press:  18 September 2015

Peter G. Barth
Peter G. Barth*
Affiliation:
Departments of Neurology and Pediatrics (Pediatric Neurology), University Hospital of Amsterdam and the Department of Neuropathology, Free University Hospital, Amsterdam, The Netherlands
*
Room G8-207, University Hospital of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
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Abstract:

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Neuronal migration constitutes one of the major processes by which the central nervous system takes shape. Detailed knowledge about this important process now exists for different brain regions in rodent and monkey models as well as in the human. In the human, distinct genetic, chromosomal and environmental causes are known that affect neuronal migration, often in a morphologically distinct pattern, but the underlying pathological mechanisms are largely unknown. This review is intended to integrate our basic knowledge of the field with the accumulated intelligence on a large number of disorders and syndromes that represent the human part of the story.

Type
Review Article
Information
Canadian Journal of Neurological Sciences , Volume 14 , Issue 1 , February 1987 , pp. 1 - 16
Copyright
Copyright © Canadian Neurological Sciences Federation 1987

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