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Studies on calcium absorption from milk using a double-label stable isotope technique

Published online by Cambridge University Press:  09 March 2007

Susan J. Fairweather-Tait ,
Amanda Johnson ,
J. Eagles ,
Smita Ganatra ,
H. Kennedy  and
M. I. Gurr
Susan J. Fairweather-Tait
Affiliation:
AFRC Institute of Food Research, Norwich Laboratory, Colney Lane, Norwich NR4 7UA
Amanda Johnson
Affiliation:
AFRC Institute of Food Research, Norwich Laboratory, Colney Lane, Norwich NR4 7UA
J. Eagles
Affiliation:
AFRC Institute of Food Research, Norwich Laboratory, Colney Lane, Norwich NR4 7UA
Smita Ganatra
Affiliation:
Milk Marketing Board, Thames Ditton, Surrey KT7 OEL
H. Kennedy
Affiliation:
West Norwich Hospital, Bowthorpe Road, Norwich NRI 3SR
M. I. Gurr
Affiliation:
Milk Marketing Board, Thames Ditton, Surrey KT7 OEL
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Abstract

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Calcium absorption was measured in ten male volunteers from skimmed milk, Ca-enriched skimmed milk or watercress (Nasturtium officinale) soup. The foods were labelled extrinsically with 30 mg 44Ca. Shortly after consuming the labelled meal, each subject was given an intravenous injection of 3 mg 42ca. Fractional absorption from the oral dose was determined from plasma and urine samples collected 24–72 h later, using fast atom bombardment mass spectrometry to measure isotope ratios. The values for urine and plasma were in good agreement. Mean percentage absorption was 45.5 (SEM 1.9)% from the skimmed milk, 35.7 (SEM 4.7) % from the Ca-enriched milk and 27.4 (SEM 1.9) % from the watercress soup. The effect of consuming 568 ml (1 pint) Ca-enriched milk each day for 4 weeks on the efficiency of absorption of Ca was studied. Although there was no statistically significant difference between Ca absorption before and after the supplementation period, the results were considered to be somewhat inconclusive due to the small number of subjects and wide individual variation in Ca absorption.

Keywords

Calcium absorptionMilk calciumDouble-label stable isotope technique
Type
Lipids
Information
British Journal of Nutrition , Volume 62 , Issue 2 , September 1989 , pp. 379 - 388
Copyright
Copyright © The Nutrition Society 1989

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