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A preliminary simulated iron fortification trial in South Indian preschool children

Published online by Cambridge University Press:  09 December 2008

Sheila M. Pereira
Affiliation:
Nutrition Research Unit and Wellcome Research Unit, Christian Medical College and Hospital, Vellore, India
Almas Begum
Affiliation:
Nutrition Research Unit and Wellcome Research Unit, Christian Medical College and Hospital, Vellore, India
V. I. Mathan
Affiliation:
Nutrition Research Unit and Wellcome Research Unit, Christian Medical College and Hospital, Vellore, India
S. J. Baker
Affiliation:
Nutrition Research Unit and Wellcome Research Unit, Christian Medical College and Hospital, Vellore, India
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Abstract

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1. The effect of fortification of food with iron to provide 10 mg elemental Fe/child per d was studied in preschool children maintained on a cereal diet, over a 5-month period.

2. The absorption of 5 mg Fe as ferrous sulphate mixed in one meal was 3.3% of the test dose and when 3.3 mg was given with each of three meals over a 2 d period the corresponding value was 4.8%.

3. The mean absorption of a test dose of ferrous ascorbate studied in twenty-four children midway through the trial was 42%.

4. The only beneficial effect of Fe fortification in this time-period in the experimental group was the prevention of the decrease in packed cell volume which occurred in the control group.

Type
Papers of direct relevance to Clinical and Human Nutrition
Copyright
Copyright © The Nutrition Society 1979

References

Bothwell, T. H. & Finch, C. A. (1962). Iron Metabolism, p. 302. London: J. & A. Churchill Ltd.Google Scholar
Cook, J. D., Layrisse, M. & Finch, C. A. (1969). Blood 33, 421.CrossRefGoogle Scholar
Cook, I. D., Minnich, B., Moore, C. V., Rasmussen, A., Bradley, W. B. & Finch, C. A. (1973). Am. J. clin. Nutr. 26, 861.CrossRefGoogle Scholar
Elvehjem, C. A. (1930). J. biol. Chem. 86,463.CrossRefGoogle Scholar
Elwood, P. C. (1968). Proc. Nutr. Soc. 27, 14.CrossRefGoogle Scholar
Herbert, V., Gottlieb, C. W., Lau, K. S., Fisher, M., Gevirtz, N. R. & Wasserman, L. R. (1966). J. Lab. clin. Med. 67, 855.Google Scholar
Hunter, S. H., Bach, M. K. & Ross, G. I. M. (1956). J. Protozool. 3, 1017.Google Scholar
International Committee for Standardization in Haematology (1971). Br. J. Haemat. 20, 451.CrossRefGoogle Scholar
Layrisse, M., Martinez-Torres, C. & Gonsalez, M. (1974). Am. J. clin. Nutr. 27, 52.CrossRefGoogle Scholar
Pereira, S. M., Almas, Begum & Baker, S. J. (1978). Br. J. Nutr. 39, 493.CrossRefGoogle Scholar
Sayers, M. H., Lynch, S. R., Charlton, R. W., Bothwell, T. H., Walker, R. B. & Mayet, F. (1974). Br. J. Nutr. 31, 367.CrossRefGoogle Scholar
Smith, C. H. (1972). In Blood Diseases of infancy and Childhood, 3rd ed. p. 15 [Smith, C. H., editor] St Louis, Miss.: C. V. Mosby Co.Google Scholar
Waters, A. H. & Molin, D. L. (1961). J. clin. Path. 14, 335.CrossRefGoogle Scholar
WHO (1975). Tech. Rep. Ser. Wld. Hlth. Org. no. 522.Google Scholar