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Physical exercise affects the lipid profile of mitochondrial membranes in rats fed with virgin olive oil or sunflower oil

Published online by Cambridge University Press:  09 March 2007

José L. Quiles ,
Jesús R. Huertas ,
Mariano Mañas ,
Maurizio Battino  and
José Mataix
José L. Quiles*
Affiliation:
Institute of Nutrition and Food Technology (INYTA)and Department of Physiology, University of Granada, Spain
Jesús R. Huertas
Affiliation:
Institute of Nutrition and Food Technology (INYTA)and Department of Physiology, University of Granada, Spain
Mariano Mañas
Affiliation:
Institute of Nutrition and Food Technology (INYTA)and Department of Physiology, University of Granada, Spain
Maurizio Battino
Affiliation:
Institute of Biochemistry, Faculty of Medicine, University of Ancona, 60131 Ancona, Italy
José Mataix
Affiliation:
Institute of Nutrition and Food Technology (INYTA)and Department of Physiology, University of Granada, Spain
*
*Corresponding author: present address, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK, fax +44 (0)1224 716687, email [email protected]
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Abstract

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The effects of physical exercise on the lipid profile in mitochondrial membranes of liver and skeletal muscle were examined in rats fed with virgin olive oil or sunflower oil. Thirty male Wistar rats, 21 d old, were randomly assigned to four groups according to fat ingestion and physical activity over an 8-week period. For each type of oil, one group acted as a control group while rats from the other were trained to run for 40 min daily on a horizontal treadmill, at a speed of 35 m/min. The results show that diet affected the fatty acid profile of the mitochondrial membranes from skeletal muscle and liver. Physical exercise also modified the fatty acid profile of the mitochondrial membranes. Total monounsaturated fatty acids decreased (P < 0.001) in liver mitochondria of exercised animals. Total polyunsaturated fatty acids in mitochondrial membranes of liver increased (P < 0.005) after exercise but those in mitochondrial membranes of skeletal muscle decreased (P < 0.05). These changes due to the exercise may arise via several mechanisms, e.g. fluidity regulation; changes in the eicosanoid metabolism; differences in the availability or oxidation rate of the different fatty acids.

Keywords

LiverSkeletal muscleDietary fatExercise
Type
Short communication
Information
British Journal of Nutrition , Volume 81 , Issue 1 , January 1999 , pp. 21 - 24
Copyright
Copyright © The Nutrition Society 1999

References

Ayre, KJ & Hulbert, AJ (1997) Dietary fatty acid profile affects endurance in rats. Lipids 32, 1265–1270.CrossRefGoogle ScholarPubMed
Giron, MDMataix, J & Suarez, MD (1992) Long-term effects of dietary monounsaturated and polyunsaturated fatty acids on the lipid composition of erythrocyte membranes in dogs. Comparative Biochemistry and Physiology 102, 197–201.CrossRefGoogle ScholarPubMed
Huertas, JRBattino, MBarzanti, VMaranesi, MParenti-Castelli, GLittarru, GPTurchetto, EMataix, FJ & Lenaz, G (1992) Mitochondrial and microsomal cholesterol mobilization after oxidative stress induced by adriamycin in rats fed with dietary olive and corn oil. Life Science 50, 2111–2118.CrossRefGoogle ScholarPubMed
Innis, SM & Clandinin, MT (1981) Dynamic modulation of mitochondrial inner-membrane lipids in rat heart by dietary fat. Biochemical Journal 193, 155–167.CrossRefGoogle ScholarPubMed
Lepage, G & Roy, CC (1986) Direct transesterification of all classes of lipids in a one-step reaction. Journal of Lipid Research 27, 114–120.CrossRefGoogle Scholar
Lewis, DEShellard, LKoeslag, DGBoer, DEMcCarthy, HMMcKibbin, PERussell, JC & Williams, G (1993) Intense exercise and food restriction cause similar hypothalamic neuropeptide Y increases in rats. American Journal of Physiology 264, E279–E284.Google Scholar
Masumura, SFurui, HHashimoto, M & Watanabe, Y (1992) The effects of season and exercise on the levels of plasma polyunsaturated fatty acids and lipoprotein cholesterol in young rats. Biochimica et Biophysica Acta 1125, 292–296.Google ScholarPubMed
Mataix, JQuiles, JLHuertas, JRBattino, M & Mañas, M (1998) Tissue specific interactions of exercise, dietary fatty acids, and vitamin E in lipid peroxidation. Free Radical Biology and Medicine 24, 511–521.Google Scholar
Periago, JLSuarez, MD & Pita, ML (1990) Effect of dietary olive oil, corn oil and medium-chain triglycerides on the lipid composition of rat red blood cell membranes. Journal of Nutrition 120, 986–994.CrossRefGoogle ScholarPubMed
Salting, B & Astrand, PO (1993) Free fatty acids and exercise. American Journal of Clinical Nutrition 57, 752S–758S.CrossRefGoogle Scholar
Seiquer, IMañas, MMartínez-Victoria, EBallesta, MC & Mataix, FJ (1996) Long-term influence of dietary fat (sunflower oil, olive oil, lard and fish oil) in the serum fatty acid composition and in the different lipidic fractions, in miniature swine. International Journal for Vitamin and Nutrition Research 66, 171–179.Google ScholarPubMed
Snedecor, GW & Cochran, WG (1980) Statistical Methods, 7th ed. Ames, IA: Iowa State University Press.Google Scholar
Suárez, ARamírez, MCDFaus, MJ & Gil, A (1996) Dietary long-chain polyunsaturated fatty acids influence tissue fatty acid composition in rats at weaning. Journal of Nutrition 126, 887–897.CrossRefGoogle ScholarPubMed
Vapaatalo, HLaustiola, KSeppala, ERauramaa, RKaste, MHillbom, M & Kangasaho, M (1984) Exercise, ethanol and arachidonic acid metabolism in healthy men. Biomedica Biochimica Acta 43, S413–S420.Google ScholarPubMed