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Physical exercise affects the lipid profile of mitochondrial membranes in rats fed with virgin olive oil or sunflower oil

Published online by Cambridge University Press:  09 March 2007

José L. Quiles ,
Jesús R. Huertas ,
Mariano Mañas ,
Maurizio Battino  and
José Mataix
José L. Quiles*
Affiliation:
Institute of Nutrition and Food Technology (INYTA)and Department of Physiology, University of Granada, Spain
Jesús R. Huertas
Affiliation:
Institute of Nutrition and Food Technology (INYTA)and Department of Physiology, University of Granada, Spain
Mariano Mañas
Affiliation:
Institute of Nutrition and Food Technology (INYTA)and Department of Physiology, University of Granada, Spain
Maurizio Battino
Affiliation:
Institute of Biochemistry, Faculty of Medicine, University of Ancona, 60131 Ancona, Italy
José Mataix
Affiliation:
Institute of Nutrition and Food Technology (INYTA)and Department of Physiology, University of Granada, Spain
*
*Corresponding author: present address, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK, fax +44 (0)1224 716687, email [email protected]
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Abstract

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The effects of physical exercise on the lipid profile in mitochondrial membranes of liver and skeletal muscle were examined in rats fed with virgin olive oil or sunflower oil. Thirty male Wistar rats, 21 d old, were randomly assigned to four groups according to fat ingestion and physical activity over an 8-week period. For each type of oil, one group acted as a control group while rats from the other were trained to run for 40 min daily on a horizontal treadmill, at a speed of 35 m/min. The results show that diet affected the fatty acid profile of the mitochondrial membranes from skeletal muscle and liver. Physical exercise also modified the fatty acid profile of the mitochondrial membranes. Total monounsaturated fatty acids decreased (P < 0.001) in liver mitochondria of exercised animals. Total polyunsaturated fatty acids in mitochondrial membranes of liver increased (P < 0.005) after exercise but those in mitochondrial membranes of skeletal muscle decreased (P < 0.05). These changes due to the exercise may arise via several mechanisms, e.g. fluidity regulation; changes in the eicosanoid metabolism; differences in the availability or oxidation rate of the different fatty acids.

Keywords

LiverSkeletal muscleDietary fatExercise
Type
Short communication
Information
British Journal of Nutrition , Volume 81 , Issue 1 , January 1999 , pp. 21 - 24
Copyright
Copyright © The Nutrition Society 1999

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