Hostname: page-component-586b7cd67f-g8jcs Total loading time: 0 Render date: 2024-11-27T21:18:43.124Z Has data issue: false hasContentIssue false

Nuts, body weight and insulin resistance

Published online by Cambridge University Press:  19 April 2007

Sujatha Rajaram*
Affiliation:
Department of Nutrition, School of Public Health, Loma Linda University, Loma Linda, CA 92350, USA
Joan Sabaté
Affiliation:
Department of Nutrition, School of Public Health, Loma Linda University, Loma Linda, CA 92350, USA
*
*Corresponding author: Sujatha Rajaram, fax 909-558-4095, email [email protected]
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Traditionally, nuts have been considered a staple food, but because of their high energy and fat content are not considered good for body weight control or insulin sensitivity. Frequent consumption of nuts reduces the risk of coronary artery disease and type-2 diabetes and nut-enriched diets favourably alter blood lipids in normal and hypercholesterolemic individuals under controlled and free-living dietary conditions. However, whether or not frequent consumption of nuts can cause weight gain and impair insulin sensitivity is not fully understood. Review of the available data to date suggests that adding nuts to habitual diets of free-living individuals does not cause weight gain. In fact, nuts have a tendency to lower body weight and fat mass. In the context of calorie-restricted diets, adding nuts produces a more lasting and greater magnitude of weight loss among obese subjects while improving insulin sensitivity. Further studies are needed to clarify the effect of long-term (≥ year) consumption of nuts on body weight and their role in altering insulin sensitivity both in normal and type-2 diabetics. In the meantime, there is sufficient evidence to promote the inclusion of nuts as part of healthy diets.

Type
Research Article
Copyright
Copyright © The Nutrition Society 2006

References

Abbey, M, Noakes, M, Belling, GB & Nestel, PJ (1994) Partial replacement of saturated fatty acids with almonds or walnuts lowers total plasma cholesterol and low-density-lipoprotein cholesterol. Am J Clin Nutr 59, 995999.CrossRefGoogle ScholarPubMed
Albert, CM, Gaziano, JM, Willett, WC & Manson, JE (2002) Nut consumption and decreased risk of sudden cardiac death in the Physicians' Health Study. Arch Intern Med 162, 13821387.CrossRefGoogle ScholarPubMed
Almario, RU, Vonghavaravat, V, Wong, R & Kasim-Karakas, SE (2001) Effects of walnut consumption on plasma fatty acids and lipoproteins in combined hyperlipidemia. Am J Clin Nutr 74, 7279.CrossRefGoogle ScholarPubMed
Alper, CM & Mattes, RD (2002) Effects of chronic peanut consumption on energy balance and hedonics. Int J Obes Relat Metab Disord 26, 11291137.Google Scholar
Chisholm, A, Mann, J, Skeaff, M, Frampton, C, Sutherland, W, Duncan, A & Tiszavari, S (1998) A diet rich in walnuts favourably influences plasma fatty acid profile in moderately hyperlipidaemic subjects. Eur J Clin Nutr 52, 1216.CrossRefGoogle Scholar
Colquhoun, DM, Humphries, JA, Moores, D & Somerset, SM (1996) Effects of a macadamia nut enriched diet on serum lipids and lipoproteins compared to a low fat diet. Food Aus 48, 216222.Google Scholar
Curb, JD, Wergowske, G, Dobbs, JC, Abbott, RD & Huang, B (2000) Serum lipid effects of a high-monounsaturated fat diet based on macadamia nuts. Arch Intern Med 160, 11541158.CrossRefGoogle ScholarPubMed
Durak, I, Koksal, I, Kacmaz, M, Buyukkocak, S, Cimen, BM & Ozturk, HS (1999) Hazelnut supplementation enhances plasma antioxidant potential and lowers plasma cholesterol levels. Clin Chim Acta 284, 113115.CrossRefGoogle ScholarPubMed
Edwards, K, Kwaw, I, Matud, J & Kurtz, I (1999) Effect of pistachio nuts on serum lipid levels in patients with moderate hypercholesterolemia. J Am Coll Nutr 18, 229232.CrossRefGoogle ScholarPubMed
Ellis, PR, Kendall, CW, Ren, Y, Parker, C, Pacy, JF, Waldron, KW & Jenkins, DJ (2004) Role of cell walls in the bioaccessibility of lipids in almond seeds. Am J Clin Nutr 80, 604613.CrossRefGoogle ScholarPubMed
Fraser, GE, Bennett, HW, Jaceldo, KB & Sabate, J (2002) Effect on body weight of a free 76 Kilojoule (320 calorie) daily supplement of almonds for six months. J Am Coll Nutr 21, 275283.CrossRefGoogle ScholarPubMed
Fraser, GE, Sabaté, J, Beeson, WL & Strahan, TM (1992) A possible protective effect of nut consumption on risk of coronary heart disease. The Adventist Health Study. Arch Intern Med 152, 14161424.CrossRefGoogle ScholarPubMed
Garcia-Lorda, P, Megias, Rangil I & Salas-Salvado, J (2003) Nut consumption, body weight and insulin resistance. Eur J Clin Nutr 57, Suppl. 1, S8S11.Google Scholar
Garg, ML, Blake, RJ & Wills, RB (2003) Macadamia nut consumption lowers plasma total and LDL cholesterol levels in hypercholesterolemic men. J Nutr 133, 10601063.CrossRefGoogle ScholarPubMed
Holt, SH, Miller, JC, Petocz, P & Farmakalidis, E (1995) A satiety index of common foods. Eur J Clin Nutr 49, 675690.Google Scholar
Hu, FB, Stampfer, MJ, Manson, JE, Rimm, EB, Colditz, GA, Rosner, BA, Speizer, FE, Hennekens, CH & Willett, WC (1998) Frequent nut consumption and risk of coronary heart disease in women: prospective cohort study. BMJ 317, 13411345.CrossRefGoogle ScholarPubMed
Hu, FB, van Dam, RM & Liu, S (2001) Diet and risk of Type II diabetes: the role of types of fat and carbohydrate. Diabetologia 44, 805817.CrossRefGoogle ScholarPubMed
Hyson, DA, Schneeman, BO & Davis, PA (2002) Almonds and almond oil have similar effects on plasma lipids and LDL oxidation in healthy men and women. J Nutr 132, 703707.CrossRefGoogle ScholarPubMed
Iwamoto, M, Imaizumi, K, Sato, M, Hirooka, Y, Sakai, K, Takeshita, A & Kono, M (2002) Serum lipid profiles in Japanese women and men during consumption of walnuts. Eur J Clin Nutr 56, 629637.CrossRefGoogle ScholarPubMed
Jaceldo-Siegl, K, Sabate, J, Rajaram, S & Fraser, GE (2004) Long-term almond supplementation without advice on food replacement induces favourable nutrient modifications to the habitual diets of free-living individuals. Br J Nutr 92, 533540.Google Scholar
Jenkins, DJ, Kendall, CW, Marchie, A, Parker, TL, Connelly, PW, Qian, W, Haight, JS, Faulkner, D, Vidgen, E, Lapsley, KG & Spiller, GA (2002) Dose response of almonds on coronary heart disease risk factors: blood lipids, oxidized low-density lipoproteins, lipoprotein(a), homocysteine, and pulmonary nitric oxide: a randomized, controlled, crossover trial. Circulation 106, 13271332.Google Scholar
Jiang, R, Manson, JE, Stampfer, MJ, Liu, S, Willett, WC & Hu, FB (2002) Nut and peanut butter consumption and risk of type 2 diabetes in women. JAMA 288, 25542560.CrossRefGoogle ScholarPubMed
Krauss, RM, Eckel, RH, Howard, B, Appel, LJ, Daniels, SR, Deckelbaum, RJ, Erdman, JW Jr, Kris-Etherton, P, Goldberg, IJ, Kotchen, TA, Lichtenstein, AH, Mitch, WE, Mullis, R, Robinson, K, Wylie-Rosett, J, St Jeor, S, Suttie, J, Tribble, DL & Bazzarre, TL (2000) AHA Dietary Guidelines: revision 2000: A statement for healthcare professionals from the Nutrition Committee of the American Heart Association. Circulation 102, 22842299.CrossRefGoogle ScholarPubMed
Kushi, LH, Folsom, AR, Prineas, RJ, Mink, PJ, Wu, Y & Bostick, RM (1996) Dietary antioxidant vitamins and death from coronary heart disease in postmenopausal women. N Engl J Med 334, 11561162.Google Scholar
Lopez-Ridaura, R, Willett, WC, Rimm, EB, Liu, S, Stampfer, MJ, Manson, JE & Hu, FB (2004) Magnesium intake and risk of type 2 diabetes in men and women. Diabetes Care 27, 134140.CrossRefGoogle ScholarPubMed
Lovejoy, JC, Most, MM, Lefevre, M, Greenway, FL & Rood, JC (2002) Effect of diets enriched in almonds on insulin action and serum lipids in adults with normal glucose tolerance or type 2 diabetes. Am J Clin Nutr 76, 10001006.CrossRefGoogle ScholarPubMed
McManus, K, Antinoro, L & Sacks, F (2001) A randomized controlled trial of a moderate-fat, low-energy diet compared with a low fat, low-energy diet for weight loss in overweight adults. Int J Obes Relat Metab Disord 25, 15031511.Google Scholar
Morgan, JM, Horton, K, Reese, D, Carey, C, Walker, K & Capuzzi, DM (2002) Effects of walnut consumption as part of a low-fat, low-cholesterol diet on serum cardiovascular risk factors. Int J Vitam Nutr Res 72, 341347.CrossRefGoogle ScholarPubMed
Morgan, WA & Clayshulte, BJ (2000) Pecans lower low-density lipoprotein cholesterol in people with normal lipid levels. J Am Diet Assoc 100, 312318.Google Scholar
Paolisso, G, Scheen, A, D'Onofrio, F & Lefebvre, P (1990) Magnesium and glucose homeostasis. Diabetologia 33, 511514.Google Scholar
Rajaram, S, Burke, K, Connell, B, Myint, T & Sabate, J (2001) A monounsaturated fatty acid-rich pecan-enriched diet favorably alters the serum lipid profile of healthy men and women. J Nutr 131, 22752279.CrossRefGoogle ScholarPubMed
Rocca, AS, LaGreca, J, Kalitsky, J & Brubaker, PL (2001) Monounsaturated fatty acid diets improve glycemic tolerance through increased secretion of glucagon-like peptide-1. Endocrinology 142, 11481155.CrossRefGoogle ScholarPubMed
Sabaté, J (1993) Does nut consumption protect against ischaemic heart disease? Eur J Clin Nutr 47, Suppl. 1S71S75.Google ScholarPubMed
Sabaté, J (2003) Nut consumption and body weight. Am J Clin Nutr 78, 647S650S.Google Scholar
Sabaté, J, Cordero-Macintyre, Z, Siapco, G, Torabian, S & Haddad, E (2005) Does regular walnut consumption lead to weight gain? Br J Nutr 94, 859864.Google Scholar
Sabaté, J, Fraser, GE, Burke, K, Knutsen, SF, Bennett, H & Lindsted, KD (1993) Effects of walnuts on serum lipid levels and blood pressure in normal men. N Engl J Med 328, 603607.CrossRefGoogle ScholarPubMed
Sabaté, J, Haddad, E, Tanzman, JS, Jambazian, P & Rajaram, S (2003) Serum lipid response to the graduated enrichment of a Step I diet with almonds: a randomized feeding trial. Am J Clin Nutr 77, 13791384.CrossRefGoogle Scholar
Salas-Salvado, J, Bullo, M, Perez-Haras, A & Ros, E (2006) Dietary Fibre, Nuts and Cardiovascular Disease. Br J Nutr 96, S45 – S51.Google Scholar
Salmeron, J, Manson, JE, Stampfer, MJ, Colditz, GA, Wing, AL & Willett, WC (1997) Dietary fiber, glycemic load, and risk of non-insulin-dependent diabetes mellitus in women. JAMA 277, 472477.Google Scholar
Schroder, H, Marrugat, J, Vila, J, Covas, MI & Elosua, R (2004) Adherence to the traditional mediterranean diet is inversely associated with body mass index and obesity in a spanish population. J Nutr 134, 33553361.CrossRefGoogle Scholar
Soriguer, FJ, Gonzalez-Romero, S, Esteva, I, Garcia-Arnes, JA, Tinahones, F, Ruiz de Adana, MS, Olveira, G, Mancha, I & Vazques, F (1995) Does the intake of nuts and seeds alter the appearance of menarche? Acta Obstet Gynecol Scand 74, 455461.Google Scholar
Spiller, GA, Jenkins, DA, Bosello, O, Gates, JE, Cragen, LN & Bruce, B (1998) Nuts and plasma lipids: an almond-based diet lowers LDL-C while preserving HDL-C. J Am Coll Nutr 17, 285290.Google Scholar
Spiller, GA, Jenkins, DJ, Cragen, LN, Gates, JE, Bosello, O, Berra, K, Rudd, C, Stevenson, M & Superko, R (1992) Effect of a diet high in monounsaturated fat from almonds on plasma cholesterol and lipoproteins. J Am Coll Nutr 11, 126130.Google Scholar
St-Onge, MP (2005) Dietary fats, teas, dairy, and nuts: potential functional foods for weight control? Am J Clin Nutr 81, 715.CrossRefGoogle ScholarPubMed
Storlien, LH, Pan, DA, Kriketos, AD, O'Connor, J, Caterson, ID, Cooney, GJ, Jenkins, AB & Baur, LA (1996) Skeletal muscle membrane lipids and insulin resistance. Lipids 31, Suppl.S261S265.CrossRefGoogle ScholarPubMed
Tapsell, LC, Gillen, LJ, Patch, CS, Batterham, M, Owen, A, Bare, M & Kennedy, M (2004) Including walnuts in a low-fat/modified-fat diet improves HDL cholesterol-to-total cholesterol ratios in patients with type 2 diabetes. Diabetes Care 27, 27772783.Google Scholar
US Department of Agriculture & Agricultural & Research Service (2000). Continuing Survey of Food Intake by Individuals 1994–96 & 1998. CSFFI CD-ROMGoogle Scholar
van Marken Lichtenbelt, WD, Mensink, RP & Westerterp, KR (1997) The effect of fat composition of the diet on energy metabolism. Z Ernahrungswiss 36, 303305.Google Scholar
Vessby, B, Unsitupa, M, Hermansen, K, Riccardi, G, Rivellese, AA, Tapsell, LC, Nalsen, C, Berglund, L, Louheranta, A, Rasmussen, BM, Calvert, GD, Maffetone, A, Pedersen, E, Gustafsson, IB & Storlien, LH (2001) Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: The KANWU Study. Diabetologia 44, 312319.Google Scholar
Wien, MA, Sabate, JM, Ikle, DN, Cole, SE & Kandeel, FR (2003) Almonds vs complex carbohydrates in a weight reduction program. Int J Obes Relat Metab Disord 27, 13651372.CrossRefGoogle Scholar
Zambon, D, Sabate, J, Munoz, S, Campero, B, Casals, E, Merlos, M, Laguna, JC & Ros, E (2000) Substituting walnuts for monounsaturated fat improves the serum lipid profile of hypercholesterolemic men and women. A randomized crossover trial. Ann Intern Med 132, 538546.Google Scholar
Zemaitis, J & Sabaté, J (2001) Effect of almond consumption on stool weight and stool fat. FASEB J 15, A602.Google Scholar