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Influence of amount of dietary fat and protein on esterase-1 (ES-1) activities of plasma and small intestine in rats

Published online by Cambridge University Press:  09 March 2007

H. A. Van Lith ,
G. W. Meijer ,
M. J. A. van der Wouw ,
M. Den Bieman ,
G. Van Tintelen ,
L. F. M. Van Zutphen  and
A. C. Beynen
H. A. Van Lith
Affiliation:
Department of Laboratory Animal Science, Veterinary Faculty, State University, PO Box 80.166, 3508 TD Utrecht
G. W. Meijer
Affiliation:
Department of Laboratory Animal Science, Veterinary Faculty, State University, PO Box 80.166, 3508 TD Utrecht
M. J. A. van der Wouw
Affiliation:
Department of Laboratory Animal Science, Veterinary Faculty, State University, PO Box 80.166, 3508 TD Utrecht
M. Den Bieman
Affiliation:
Department of Laboratory Animal Science, Veterinary Faculty, State University, PO Box 80.166, 3508 TD Utrecht
G. Van Tintelen
Affiliation:
Laboratory Animals Centre Agricultural University, PO Box 8129, 6700 EV Wageningen, The Netherlands
L. F. M. Van Zutphen
Affiliation:
Department of Laboratory Animal Science, Veterinary Faculty, State University, PO Box 80.166, 3508 TD Utrecht
A. C. Beynen
Affiliation:
Department of Laboratory Animal Science, Veterinary Faculty, State University, PO Box 80.166, 3508 TD Utrecht Department of Human Nutrition, Agricultural University, PO Box 8129, 6700 EV Wageningen, The Netherlands
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Abstract

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The objective of the present study was to characterize nutritionally esterase-1 (ES-1). For this purpose, the effects of replacement of dietary carbohydrates by isoenergetic amounts of either fat or protein on ES-1 activities of plasma and small intestine were studied in male rats. Purified diets differing in the amounts of maize starch plus dextrose, casein and various types of fat were used. Plasma and jejunal ES-1 activities were found to be increased with increasing fat intakes. As to the type of fat, increasing plasma ES-1 activities were induced by coconut fat, olive oil, maize oil and medium-chain triacylglycerols, in this order. Maize oil induced higher jejunal ES-1 activities than coconut fat and olive oil, but had similar effects to medium-chain triacylglycerols. Maize oil was more powerful in increasing plasma ES-1 activity than isoenergetic amounts of casein, but with respect to jejunal ES-1 activity these dietary components were equally effective. It is concluded that the amounts of fat and protein in the diet are important determinants of ES-1 activities in plasma and jejunum.

Keywords

Dietary fatEsterase-1PlasmaIntestineRat
Type
Metabolic Effects of Diet
Information
British Journal of Nutrition , Volume 67 , Issue 3 , May 1992 , pp. 379 - 390
Copyright
Copyright © The Nutrition Society 1992

References

REFERENCES

Augustinsson, K. B. & Henricson, B. (1966) A genetically controlled esterase in rat plasma. Biochimica et Biophysica Acta 124, 323–331.CrossRefGoogle ScholarPubMed
Beynen, A. C. (1987) Serum and liver cholesterol in rats fed cholesterol-free or high-cholesterol diets differing in type and amount of fat. Nutrition Reports International 35, 1327–1332.Google Scholar
Beynen, A. C., Lemmens, A. G., Katan, M. B., De Bruijne, J. J. & Van Zutphen, L. F. M. (1987) Cholesterol metabolism and esterases in four strains of rats with differential cholesterolemic responses to a high-cholesterol, high-cholate diet. Comparative Biochemistry and Physiology 87 B, 41–48.Google Scholar
Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72, 248–254.CrossRefGoogle ScholarPubMed
Folch, J., Lees, M. & Sloane-Stanley, G. H. (1957) A simple method for the isolation and purification of total lipids from animal tissues. Journal of Biological Chemistry 266, 497–509.CrossRefGoogle Scholar
Krisch, K. (1971). Carboxylic ester hydrolases. In The Enzymes, Vol. 5, pp. 43–49 [Boyer, P. D., editor]. New York and London: Academic Press.Google Scholar
Lewis, A. A. M. & Hunter, R. L. (1966) The effect of fat ingestion on the esterase isozymes of intestine, intestinal lymph and serum. Journal of Histochemistry and Cytochemistry 14, 33–39.CrossRefGoogle ScholarPubMed
Mentlein, R. & Heymann, E. (1984) Hydrolysis of ester- and amide-type drugs by the purified isoenzymes of nonspecific carboxylesterase from rat liver. Biochemical Pharmacology 33, 1243–1248.CrossRefGoogle ScholarPubMed
Mentlein, R., Suttorp, M. & Heymann, E. (1985) Specificity of purified monoacylglycerol lipase, palmitoyl-CoA hydrolase, palmitoyl-carnitine hydrolase and nonspecific carboxylesterase from rat liver microsomes. Archives of Biochemistry and Biophysics 228, 230–246.CrossRefGoogle Scholar
Metcalfe, L. D., Schmitz, A. A. & Pelka, J. R. (1966) Rapid preparation of fatty acid esters from lipids for gas chromatography analysis. Analytical Chemistry 18, 514–515.CrossRefGoogle Scholar
Osborne, D. R. & Voogt, P. (1978) The Analysis of Nutrients in Food. London: Academic Press.Google Scholar
SPSS/PC + (1988) Stastistical Package for the Social Sciences: Base Manual V 2.0. Chicago, USA: SPSS Inc.Google Scholar
Van Lith, H. A., Meijer, G. W., Van Zutphen, L. F. M. & Beynen, A. C. (1989) Plasma esterase-1 (ES-1) activity is increased in rats fed high-fat diets. Lipids 24, 86–88.CrossRefGoogle ScholarPubMed
Van Zutphen, L. F. M. & Den Bieman, M. G. C. W. (1988). Gene mapping and linkage homology. In New Developments in Biosciences: Their Implications for Laboratory Animal Science, pp. 197–200 [Beynen, A.C. and Solleveld, H. A., editors]. Dordrecht, The Netherlands: Martinus Nijhoff Publishers.CrossRefGoogle Scholar
Wassmer, B., Augenstein, U., Ronai, A., De Looze, S. & Von Deimling, O. (1988) Lymph esterases of the house mouse (Mus musculus)-II. The role of esterase-2 in fat resorption. Comparative Biochemistry and Physiology 91 B, 179–185.Google Scholar