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Dietary intakes and adipose tissue levels of linoleic acid in peptic ulcer disease

Published online by Cambridge University Press:  09 March 2007

J. Kearney ,
N. P. Kennedy ,
P. W. N. Keeling ,
J. J. Keating ,
Louise Grubb ,
Margaret Kennedy  and
M. J. Gibney
J. Kearney
Affiliation:
Division of Nutritional Sciences, Department of Clinical Medicine, Trinity College Medical School, St James's Hospital, Dublin 8, Republic of Ireland
N. P. Kennedy
Affiliation:
Division of Nutritional Sciences, Department of Clinical Medicine, Trinity College Medical School, St James's Hospital, Dublin 8, Republic of Ireland
P. W. N. Keeling
Affiliation:
Division of Nutritional Sciences, Department of Clinical Medicine, Trinity College Medical School, St James's Hospital, Dublin 8, Republic of Ireland
J. J. Keating
Affiliation:
Division of Nutritional Sciences, Department of Clinical Medicine, Trinity College Medical School, St James's Hospital, Dublin 8, Republic of Ireland
Louise Grubb
Affiliation:
Division of Nutritional Sciences, Department of Clinical Medicine, Trinity College Medical School, St James's Hospital, Dublin 8, Republic of Ireland
Margaret Kennedy
Affiliation:
Division of Nutritional Sciences, Department of Clinical Medicine, Trinity College Medical School, St James's Hospital, Dublin 8, Republic of Ireland
M. J. Gibney
Affiliation:
Division of Nutritional Sciences, Department of Clinical Medicine, Trinity College Medical School, St James's Hospital, Dublin 8, Republic of Ireland
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Abstract

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Adipose tissue levels of linoleic acid were determined from biopsies of subcutaneous abdominal fat of normal healthy controls (n 40) and from two patient groups with endoscopically evaluated non-ulcer dyspepsia (n 40) or peptic ulcer disease (n 38). The level (g/100 g) of adipose tissue linoleic acid in the normal healthy controls (15·0 (sd 4·1)) was significantly (P < 0·05) greater than that in patients with non-ulcer dyspepsia (12·8 (sd 3·5)) and in patients with peptic ulcer disease (11·7 (sd 2·7)). A dietary history revealed a lower intake of linoleic acid and a significantly (P < 0·05) lower intake of dietary fibre (g/d) for both the non-ulcer dyspepsia (15·9 (sd 6·2)) and peptic ulcer disease (15·2 (sd 7·8)) patients compared with normal healthy controls (20·2 (sd 11·2)). Adipose tissue linoleic acid tended to increase with indices of increasing socioeconomic status, although the differences between patient and controls were not confounded by socioeconomic status. Patients with dyspepsia reported more foods causing symptoms (onion, fried foods, alcohol, citrus fruits and spices) and more foods giving relief (milk, bread) compared with control orthopaedic patients.

Keywords

Linoleic acidAdipose tissuePeptic ulcer
Type
Tissue Lipids
Information
British Journal of Nutrition , Volume 62 , Issue 3 , November 1989 , pp. 699 - 706
Copyright
Copyright © The Nutrition Society 1989

References

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