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Bile acid and cholesterol excretion in human beings given soya-bean-and meat-protein-based diets: a study in ileostomy subjects

Published online by Cambridge University Press:  09 March 2007

Ingvar Bosaeus*
Affiliation:
Dept of Clinical Nutrition, University of Gothenburg, Sahlgren's Hospital, S-413 45 Gothenburg, Sweden
Brittmarie Sandström
Affiliation:
Dept of Clinical Nutrition, University of Gothenburg, Sahlgren's Hospital, S-413 45 Gothenburg, Sweden
Henrik Andersson
Affiliation:
Dept of Clinical Nutrition, University of Gothenburg, Sahlgren's Hospital, S-413 45 Gothenburg, Sweden
*
Address for correspondence: Dr I. Bosaeus, Dept of Clinical Nutrition, Sahlgren's Hospital, Annedalsklinikerna, S-413 45 Gothenburg, Sweden.
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Abstract

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1. The effect of partial replacement of meat protein with three different soya-bean-protein products on bile acid and cholesterol excretion was studied in seven ileostomy subjects. Four different test diets containing 60 g meat, rice and bread protein, or a replacement of 250 g protein/kg total dietary protein by soya-bean protein from soya-bean flour, soya-bean concentrate or soya-bean isolate, were randomly assigned to the subjects in 2-d periods.

2. Ileostomy contents were collected at 2-h intervals during the day and in one portion during the night, and immediately deep-frozen to avoid bacteriological degradation. Bile acids and cholesterol were quantified by gas-liquid chromatography.

3. No difference in daily excretion of bile acids and cholesterol was noted between test diets. Ileostomy sterol concentrations were lower when soya-bean products were fed.

4. Incorporation of moderate amounts of soya-bean products in solid diets does not seem to affect short-term sterol balance in man.

Type
Clinical and Human Nutrition Papers Studies in Man
Copyright
Copyright © The Nutrition Society 1988

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