GOCCHI – Contact Details
Country
Chile
Chairman
Dr J. Gutiérrez, GOCCHI, Chilean Cooperative Group for Oncologic Research, Eliodoro Yánez 2967, Depto. 41, Providencia, SANTIAGO, CHILE. Tel: +56 2 233 0798 Fax: +56 2 231 0983 Email: [email protected]
Vice-Chairwoman
Dr L. Bronfman, Email: [email protected]
Scientific Director
Dr R. Arriagada, Email: [email protected]
Secretary
Dr R. Schwartz, Email:[email protected]
Treasurer
Dr A. Pinto, Email: [email protected]
Directors
Dr N. Aliaga, Email: [email protected]
Dr R. Baeza, Email: [email protected]
Dr A. Corvalán, Email: [email protected]
Dr C. del Castillo, Email: [email protected]
Dr J. Madrid, Email: [email protected]
Dr A. Majlis, Email: [email protected]
Dr B. Müller, Email: [email protected]
Dr Peralta, Email: [email protected]
Dr C. Ramos, Email: [email protected]
Data Manager
Ms M. Zúñiga, Email: [email protected]
Regulatory Trials Coordinator
Mrs M.F. Chinchón, Email: [email protected]
CRA
Mrs. C. Mariani, Email: [email protected]
Accountant and Computer Programmer
Mr C. Díaz, Email: [email protected]
Website
Title
Molecular marker for dissemination in breast carcinoma.
Coordinator(s)
Dr J. Gutiérrez, GOCCHI, Chilean Cooperative Group for Oncologic Research, Eliodoro Yánez 2967, Depto. 41, Providencia, SANTIAGO, CHILE. Tel: +56 2 233 0798 Fax: +56 2 231 0983 Email: [email protected]
Dr A. Corvalán, Department of Pathology, Catholic University of Chile, 85 Lira St, SANTIAGO, CHILE. Email: [email protected]
Summary
- To identified specific oncogenes and tumor supressor genes in 10 retrospectively collected breast carcinomas, 5 without lymph node metastases and 5 with lymph node metastases using cDNA microarray technology. The five most relevant genes will be confirmed by RealTime PCR and tumour suppressor genes with significant down regulation will be evaluated for epigenetic inactivation. If confirmed, plasma from independent group of cases will be tested for selected genes for evaluation as clinical markers for dissemination.
Scheme
None available
Update
- Started March 2005; proposed end date, December 2007.
Related Publications
Abstract presented at the Latin American Congress of Breast Cancer, November 2005, Santiago, Chile.
Topics
- Breast carcinoma
- Epigenetics
- Methylation
Keywords
Breast carcinoma, molecular markers, RealTime PCR