Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-24T03:39:43.789Z Has data issue: false hasContentIssue false

Changing maladaptive memories through reconsolidation: A role for sleep in psychotherapy?

Published online by Cambridge University Press:  08 June 2015

Susanne Diekelmann
Affiliation:
Institute of Medical Psychology and Behavioral Neurobiology, University of Tübingen, Tübingen 72076, [email protected]://www.medizin.uni-tuebingen.de/en/Research/Institutes/Medical+Psychology.html
Cecilia Forcato
Affiliation:
University of Buenos Aires, Institute of Physiology, Molecular Biology and Neuroscience (IFIByNE-CONICET), 1428 Capital Federal, Buenos Aires, [email protected]

Abstract

Like Lane et al., we believe that change in psychotherapy comes about by updating dysfunctional memories with new adaptive experiences. We suggest that sleep is essential to (re-)consolidate such corrective experiences. Sleep is well-known to strengthen and integrate new memories into pre-existing networks. Targeted sleep interventions might be promising tools to boost this process and thereby increase therapy effectiveness.

Type
Open Peer Commentary
Copyright
Copyright © Cambridge University Press 2015 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Barnes, D. C. & Wilson, D. A. (2014) Slow-wave sleep-imposed replay modulates both strength and precision of memory. Journal of Neuroscience 34:5134–42.Google Scholar
Diekelmann, S. (2014) Sleep for cognitive enhancement. Front Systems Neuroscience 8:46.Google Scholar
Diekelmann, S., Biggel, S., Rasch, B. & Born, J. (2012) Offline consolidation of memory varies with time in slow wave sleep and can be accelerated by cuing memory reactivations. Neurobiology of Learning and Memory 98:103–11.Google Scholar
Diekelmann, S. & Born, J. (2010) The memory function of sleep. Nature Reviews Neuroscience 11:114–26.Google Scholar
Ellenbogen, J. M., Hu, P. T., Payne, J. D., Titone, D. & Walker, M. P. (2007) Human relational memory requires time and sleep. Proceedings of the National Academy of Sciences of the USA 104:7723–28.Google Scholar
Feld, G. B., Besedovsky, L., Kaida, K., Münte, T. F. & Born, J. (2014) Dopamine D2-like receptor activation wipes out preferential consolidation of high over low reward memories in human sleep. Journal of Cognitive Neuroscience 26(10): 2310–20.Google Scholar
Feld, G. B., Lange, T., Gais, S. & Born, J. (2013) Sleep-dependent declarative memory consolidation – unaffected after blocking NMDA or AMPA receptors but enhanced by NMDA coagonist D-cycloserine. Neuropsychopharmacology 38:2688–97.Google Scholar
Gais, S., Lucas, B. & Born, J. (2006) Sleep after learning aids memory recall. Learning and memory 13:259–62.Google Scholar
Gais, S., Rasch, B., Dahmen, J. C., Sara, S. & Born, J. (2011) The memory function of noradrenergic activity in non-REM sleep. Journal of Cognitive Neuroscience 23:2582–92.Google Scholar
Germain, A. (2013) Sleep disturbances as the hallmark of PTSD: Where are we now? American Journal of Psychiatry 170:372–82.Google Scholar
Goder, R., Baier, P. C., Beith, B., Baecker, C., Seeck-Hirschner, M., Junghanns, K. & Marshall, L. (2013) Effects of transcranial direct current stimulation during sleep on memory performance in patients with schizophrenia. Schizophrenia Research 144:153–54.Google Scholar
Goder, R., Boigs, M., Braun, S., Friege, L., Fritzer, G., Aldenhoff, J. B. & Hinze-Selch, D. (2004) Impairment of visuospatial memory is associated with decreased slow wave sleep in schizophrenia. Journal of Psychiatric Research 38:591–99.CrossRefGoogle ScholarPubMed
Hauner, K. K., Howard, J. D., Zelano, C. & Gottfried, J. A. (2013) Stimulus-specific enhancement of fear extinction during slow-wave sleep. Nature Neuroscience 16:1553–55.Google Scholar
Kaestner, E. J., Wixted, J. T. & Mednick, S. C. (2013) Pharmacologically increasing sleep spindles enhances recognition for negative and high-arousal memories. Journal of Cognitive Neuroscience 25:1597–610.Google Scholar
Kleim, B., Wilhelm, F. H., Temp, L., Margraf, J., Wiederhold, B. K. & Rasch, B. (2014) Sleep enhances exposure therapy. Psychological Medicine 44(7):1511–19.Google Scholar
Lahl, O., Wispel, C., Willigens, B. & Pietrowsky, R. (2008) An ultra short episode of sleep is sufficient to promote declarative memory performance. Journal of Sleep Research 17:310.Google Scholar
Landmann, N., Kuhn, M., Piosczyk, H., Feige, B., Baglioni, C., Spiegelhalder, K., Frase, L., Riemann, D., Sterr, A. & Nissen, C. (2014) The reorganisation of memory during sleep. Sleep Medicine Reviews 18(6):531–41.CrossRefGoogle ScholarPubMed
Lewis, P. A. & Durrant, S. J. (2011) Overlapping memory replay during sleep builds cognitive schemata. Trends in Cognitive Sciences 15:343–51.Google Scholar
Lu, W. & Goder, R. (2012) Does abnormal non-rapid eye movement sleep impair declarative memory consolidation?: Disturbed thalamic functions in sleep and memory processing. Sleep Medicine Review 16:389–94.Google Scholar
Marshall, L., Helgadottir, H., Molle, M. & Born, J. (2006) Boosting slow oscillations during sleep potentiates memory. Nature 444:610–13.Google Scholar
Mednick, S., Nakayama, K. & Stickgold, R. (2003) Sleep-dependent learning: A nap is as good as a night. Nature Neuroscience 6:697–98.Google Scholar
Ngo, H. V., Martinetz, T., Born, J. & Molle, M. (2013) Auditory closed-loop stimulation of the sleep slow oscillation enhances memory. Neuron 78:545–53.CrossRefGoogle ScholarPubMed
Oudiette, D. & Paller, K. A. (2013) Upgrading the sleeping brain with targeted memory reactivation. Trends in Cognitive Sciences 17:142–49.Google Scholar
Pace-Schott, E. F., Verga, P. W., Bennett, T. S. & Spencer, R. M. (2012) Sleep promotes consolidation and generalization of extinction learning in simulated exposure therapy for spider fear. Journal of Psychiatric Research 46:1036–44.Google Scholar
Payne, J. D. & Kensinger, E. A. (2010) Sleep's role in the consolidation of emotional episodic memories. Current Directions in Psychological Science 19:290–95.Google Scholar
Rasch, B. & Born, J. (2013) About sleep's role in memory. Physiological Reviews 93:681766.Google Scholar
Rasch, B., Buchel, C., Gais, S. & Born, J. (2007) Odor cues during slow-wave sleep prompt declarative memory consolidation. Science 315:1426–29.Google Scholar
Rolls, A., Makam, M., Kroeger, D., Colas, D., de Lecea, L. & Heller, H. C. (2013) Sleep to forget: Interference of fear memories during sleep. Molecular Psychiatry 18:1166–70.Google Scholar
Rudoy, J. D., Voss, J. L., Westerberg, C. E. & Paller, K. A. (2009) Strengthening individual memories by reactivating them during sleep. Science 326:1079.CrossRefGoogle ScholarPubMed
Schonauer, M., Geisler, T. & Gais, S. (2014) Strengthening procedural memories by reactivation in sleep. Journal of Cognitive Neuroscience 26:143–53.CrossRefGoogle ScholarPubMed
Spiers, H. J. & Bendor, D. (2014) Enhance, delete, incept: Manipulating hippocampus-dependent memories. Brain Research Bulletin 105:27.Google Scholar
Steiger, A., Dresler, M., Kluge, M. & Schussler, P. (2013) Pathology of sleep, hormones and depression. Pharmacopsychiatry 46(S1):S3035.Google Scholar
Stickgold, R., James, L. & Hobson, J. A. (2000) Visual discrimination learning requires sleep after training. Nature Neuroscience 3:1237–38.Google Scholar
Stickgold, R. & Walker, M. P. (2013) Sleep-dependent memory triage: Evolving generalization through selective processing. Nature Neuroscience 16:139–45.Google Scholar
Tamminen, J., Lambon Ralph, M. A. & Lewis, P. A. (2013) The role of sleep spindles and slow-wave activity in integrating new information in semantic memory. Journal of Neuroscience 33:15376–81.Google Scholar
Tononi, G. & Cirelli, C. (2014) Sleep and the price of plasticity: From synaptic and cellular homeostasis to memory consolidation and integration. Neuron 81:1234.Google Scholar
Tucker, M. A., Hirota, Y., Wamsley, E. J., Lau, H., Chaklader, A. & Fishbein, W. (2006) A daytime nap containing solely non-REM sleep enhances declarative but not procedural memory. Neurobiology of Learning and Memory 86:241–47.Google Scholar
Walker, M. P., Brakefield, T., Hobson, J. A. & Stickgold, R. (2003) Dissociable stages of human memory consolidation and reconsolidation. Nature 425:616–20.CrossRefGoogle ScholarPubMed