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Does the form of akinetic mutism linked to mesodiencephalic injuries bridge the double dissociation of Parkinson's disease and catatonia?

Published online by Cambridge University Press:  11 August 2003

Ayeesha K. Kamal  and
Nicholas D. Schiff
Ayeesha K. Kamal
Affiliation:
Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, NY 10021 [email protected]@med.cornell.edu
Nicholas D. Schiff
Affiliation:
Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, NY 10021 [email protected]@med.cornell.edu
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Abstract

Northoff provides a compelling argument supporting a kind of “double dissociation” of Parkinson's disease and catatonia. We discuss a related form of akinetic mutism linked to mesodiencephalic injuries and suggest an alternative to the proposed “horizontal” versus “vertical” modulation distinction. Rather than a “directional” difference in patterned neuronal activity, we propose that both disorders reflect hypersynchrony within typically interdependent but segregated networks facilitated by a common thalamic gating mechanism.

Type
Brief Report
Information
Behavioral and Brain Sciences , Volume 25 , Issue 5 , October 2002 , pp. 586 - 587
Copyright
© 2002 Cambridge University Press

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