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Creativity, psychosis, autism, and the social brain

Published online by Cambridge University Press:  26 June 2008

Michael Fitzgerald
Affiliation:
Department of Psychiatry, Trinity College, Dublin 2, Ireland. [email protected]://www.medicine.tcd.ie/psychiatry/[email protected]://www.medicine.tcd.ie/psychiatry/research/neuropsychiatry/
Ziarih Hawi
Affiliation:
Department of Psychiatry, Trinity College, Dublin 2, Ireland. [email protected]://www.medicine.tcd.ie/psychiatry/[email protected]://www.medicine.tcd.ie/psychiatry/research/neuropsychiatry/

Abstract

In the target article, Crespi & Badcock (C&B) propose a novel hypothesis based on observations that a large set of phenotypic traits exhibit diametrically opposite phenotypes in autism-spectrum versus psychotic-spectrum conditions. They propose that development of these conditions is mediated in part by alterations in “genomic imprinting.” This hypothesis is based on the model of the Prader-Willi and Angelman syndromes. The authors have produced a masterful discussion of the differences between psychosis and autism. Of course, another article could be written on the similarities.

Type
Open Peer Commentary
Copyright
Copyright © Cambridge University Press 2008

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References

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