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A review of recent information on the Haplosporidia, with special reference to Haplosporidium nelsoni (MSX disease)

Published online by Cambridge University Press:  15 December 2004

Eugene M. Burreson  and
Susan E. Ford
Eugene M. Burreson
Affiliation:
Virginia Institute of Marine Science, College of William and Mary, Gloucester Point, Virginia 23062, USA
Susan E. Ford
Affiliation:
Haskin Shellfish Research Laboratory, Rutgers University, Port Norris, New Jersey 08349, USA
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Abstract

The current status of the Haplosporidia is reviewed as well as recent information on Haplosporidium nelsoni, the causative agent of MSX disease in oysters. Recent molecular phylogenetic analyses with greatly increased taxon sampling support monophyly of the Haplosporidia and hypothesize placement of the group as sister taxon to the phylum Cercozoa. Oyster pathogens in the genus Bonamia should be considered haplosporidians based on molecular sequence data. Thus, the group contains 4 genera: Uropsoridium, Haplosporidium, Bonamia and Minchinia. Molecular phylogenetic analyses support monophyly of Urosporidium, Bonamia and Minchinia, but Haplosporidium forms a paraphyletic clade. Reports of haplosporidia worldwide are reviewed. Molecular detection assays have greatly increased our ability to rapidly and specifically diagnose important pathogens in the phylum and have also improved our understanding of the distribution and biology of H. nelsoni and H. costale. Much of the data available for H. nelsoni has been integrated into a mathematical model of host/parasite/environment interactions. Model simulations support hypotheses that recent H. nelsoni outbreaks in the NE United States are related to increased winter temperatures, and that a host other than oysters is involved in the life cycle. Evidence is presented that natural resistance to H. nelsoni has developed in oysters in Delaware Bay, USA. However, in Chesapeake Bay, USA H. nelsoni has intensified in historically low salinity areas where salinities have increased because of recent drought conditions. Efforts to mitigate the impact of H. nelsoni involve selective breeding programs for disease resistance and the evaluation of disease resistant non-native oysters.

Keywords

PhylogenyDiagnosticsNumerical modelHaplosporidiaHaplosporidium nelsoni
Type
Research Article
Information
Aquatic Living Resources , Volume 17 , Issue 4: Bivalve Diseases , October 2004 , pp. 499 - 517
Copyright
© EDP Sciences, IFREMER, IRD, 2004

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