Hostname: page-component-cd9895bd7-gvvz8 Total loading time: 0 Render date: 2024-12-25T01:01:08.908Z Has data issue: false hasContentIssue false
  • English
  • Français

Virus et Hérédité. Importance de leurs rapports dans le domaine ophtalmologique avec regard au Trachome du point de vue génétique*

Published online by Cambridge University Press:  01 August 2014

G. B. Bietti ,
L. Gedda ,
R. Vozza  and
G. Brenci
G. B. Bietti
Affiliation:
Clinica Oculistica dell'Universitá, Roma (Italia) Istituto di Genetica Medica e Gemellologia, «Gregorio Mendel» Roma (Italia)
L. Gedda
Affiliation:
Clinica Oculistica dell'Universitá, Roma (Italia) Istituto di Genetica Medica e Gemellologia, «Gregorio Mendel» Roma (Italia)
R. Vozza
Affiliation:
Clinica Oculistica dell'Universitá, Roma (Italia) Istituto di Genetica Medica e Gemellologia, «Gregorio Mendel» Roma (Italia)
G. Brenci
Affiliation:
Clinica Oculistica dell'Universitá, Roma (Italia) Istituto di Genetica Medica e Gemellologia, «Gregorio Mendel» Roma (Italia)

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Heredity in viroses has to be considered (i) from the standpoint of the specific virus which, like any living organism, presents heredity, variability and mutation, and (ii) from the standpoint of the human host, where the receptive conditions may be genetically controlled.

The heredity of disposition to poliomyelitis is also witnessed by the results of Gedda's twin clinical method as well as by the proportionality between the consanguinity ratio and the ratio of concordance of the infection in the family.

The heredity of disposition to trachoma has been studied in 775 families from Eritrea, the disease having been examined in parents and children. Statistic and genealogic analysis shows the existence of a disposition. The mating of an affected father to a nonaffected mother does not alter the frequency of the affection in the children, as compared to the case of the children of both nonaffected parents. On the other hand the affected father makes the frequency of the affection significantly rise in the children when mated to an affected mother. Such a behaviour is explained through a more frequent disposition in the children of parents both affected by one and the same disposition.

The study of the sample through the dimensions of the sibship, showing a constant nonaffected-affected ratio, independently from the above dimensions, also leads to assuming the existence of a disposition. This sharply contrasts with the epidemiologic concept of a higher risk, the higher the number of sibs.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 14 , Issue 4 , October 1965 , pp. 337 - 352
Copyright
Copyright © The International Society for Twin Studies 1965

Footnotes

*

Relation présentée au Congrès International de Neuro-Génétique (Albi, 27-30 mai 1965).

References

Bibliographie

Addair, J., Snyder, L.H. (1942). Evidence for an autosomal recessive gene for susceptibility to paralytic poliomyelitis. J. Hered., 33: 306–309.Google Scholar
Andreoni, G., Gionta, D. (1962). Il carattere di secretore salivare nei poliomielitici non vaccinati e nei poliomielitici vaccinati con vaccino Salk. G. Mal. Infett., 14: 611–612.Google Scholar
Angela, G.C. (1957). L'infezione polio nelle due correlazioni anat.-cliniche. Ed. Minewa Med., Torino.Google Scholar
Angela, G.C., Di Nola, F. et al. (1954). Epidemiologia della poliomielite anteriore acuta. Nota II. L'iperrecettività, possibile momento determinante della malattia nell'adulto. G. Mal. Infett., 6: 337–339.Google Scholar
Angela, G.C., Di Nola, F., Polistina, C. (1954). Epidemiologia della poliomielite anteriore acuta. I. Considerazioni su alcuni fattori predisponenti all'infezione poliomielitica. G. Mal. Infett., 6: 3–8.Google Scholar
Aycock, W.L. (1942). Familial aggregation in poliomyelitis. Amer. J. Med. Sci., 203: 452–465.Google Scholar
Bastin, R., Goulon, M. (1954). Forme familiari della poliomielite. Tre casi di cui due a localizzazione bulbo-protuberanziale. Minerva Med., 45: 1521–1525.Google Scholar
Bietti, G.B. (1953). Le trachome. Progr. Ophtal., 2: 232.Google Scholar
Bietti, G.B., Vozza, R. (1963). Le trachome. Progr. Ophtal., 13: 132.Google Scholar
Cattaneo, D. (1931). Tracoma e costituzione. Studi Sassari, 9: 167.Google Scholar
Dadone, G. (1954). Contributo casistico sulla poliomielite nei gemelli. G. Mal. Infett., 6: 331–332.Google Scholar
Dadone, G. (1955). Poliomielite anteriore acuta e gemellarità. Min. Nipiol., 2: 44–49.Google Scholar
De Mattia, R., Angela, G.C. et al. (1955). Considerazioni sulla fatica quale fattore predisponente alla poliomielite. Minerva Med., 2: 3–4.Google Scholar
Di Raimondo, F. (1965). Paradigmi sperimentali e clinici della ereditarietà in infettivologia. In corso di stampa.Google Scholar
Di Raimondo, F., Spaini, P. (1964). Eredità e risposta immunitaria nel paradigma gemellare. G. Mal. Infett. 16: 348–353.Google Scholar
Felici, A., Renna, N. et al. (1962). L'infezione tracomatosa sperimentale. R.C. Ist. Sup. San., 25: 447.Google Scholar
Fox, M.J., Chamberlain, J. (1953). Four fatal cases of bulbar poliomyelitis in one family. J.A.M.A., 151: 1099–1101.CrossRefGoogle ScholarPubMed
Francis, T., Krill, C. et al. (1942). Poliomyelitis following tonsillectomy in five members of a family. J.A.M.A., 119: 1392–1396.Google Scholar
Gajdusek, D.C. (1962). Kuru: an appraisal of five years of investigation. Eugen. Quart., 9: 69.Google Scholar
Gajdusek, D.C. (1963). Kuru. Trans. R. Soc. Trop. Med. Nyg., 57: 151.Google Scholar
Gajdusek, D.C., Zigas, (1957). Degenerative disease of the central nervous system in New Guinea. New Engl. J. Med., 257: 974.Google Scholar
Gedda, L. (1951) Studio dei gemelli. Ed. Orizzonte Medico, Roma.Google Scholar
Gedda, L. (1958). Genetica della tubercolosi e dei tumori. Ed. Istituto Mendel, Roma.Google Scholar
Gedda, L. (1963). On the statistical significance of one pair of MZ twins in clinical genetics. A.Ge.Me.Ge., XII: 4.Google Scholar
Gedda, L. (1965). Introduzione alla genetica infettivologica. In corso di stampa.Google Scholar
Gedda, L. Bolognesi, M. et al. (1964). Ricerche di genetica sulla silicosi dei minatori della Sardegna. Lavoro Umano, XVI: 11.Google Scholar
Genovese, V., Ricci, G. (1958). Aspetti attuali della poliomielite. Agg. Mal. Infett., 4: 261–264.Google Scholar
Gionta, D. (1959). Poliomielite e gruppi sanguigni. Med. Sperim., 37: 391–399.Google Scholar
Gionta, D., Marioni, R. (1960). Osservazioni su una coppia di fratelli mononati, affetti da epidermolisi bollosa semplice e da poliomielite anteriore acuta. A.Ge.Me.Ge., IX: 442–445.Google Scholar
Hadlow, W.J. (1959). Scrapie and Kuru. Lancet, 11: 7079.Google Scholar
Herndon, C., Jennings, R. (1951). A twin family study of susceptibility to poliomyelititis. Amer. J. Hum. Genet., 3: 17–46.Google Scholar
Hofman, B. (1954). A receptor-destroying enzyme in human saliva and its possible relation to poliomyelitis infection. J. Immunol., 73: 273–277.Google Scholar
Kennedy, J.M. (1951). Four cases of acute poliomyelitis in the same family. Lancet, 2: 1178–1179.Google Scholar
Kohn-Kony, M., Raphael, E.R. (1953). Rev Int. Track., 30: 234.Google Scholar
Lumbroso, B.D. (1964). Trachome et terrain. Rev. Int. Track., 91: 367.Google Scholar
Luria, , Delbrück, (1943). Mutations of bacteria from virus sensitivity to virus resitance. Genetics, 28: 491–511.Google Scholar
Mallardi, A. (1954). Vedute epidemiologiche sulla poliomielite. Il lattante, 25: 352–359.Google Scholar
Masini, T. (1953). Predisposizione generale e locale alla poliomielite anteriore acuta nei gemelli. Folia Hered. Pathol., 2: 115–135.Google Scholar
McAlpine, (1938). Brain, 61: 430.Google Scholar
Messeri, E. (1946). Alcune considerazioni cliniche su un caso di malattia di Heine-Medin in una coppia di gemelli monocori. Riv. Clin. Pediat., 44: 100–108.Google Scholar
Messeri, E. (1949). Riv. Clin. Pediat., 9: 541–548.Google Scholar
Murano, G., Cocozza, G. (1954). Rilievi statistico-clinici sulla poliomielite nel primo anno di vita. G. Mal. Infett., 6: 280–285.Google Scholar
Rainero, I., Terragna, A. (1959). Esiste un fattore genetico predisponente alla poliomielite? Inform. Med., 14: 493–498.Google Scholar
Russo, A. (1958), Osservazione di poliomietite anteriore acuta in gemelli. Agg. Pediat., 9: 359–365.Google Scholar
Russo, A., Romani, L. (1959). Osservazione di poliomielite anteriore acuta in gemelli. Minerva Nipiol., 9: 55–56.Google Scholar
Selvin, S. (1962). Excerpta Med., 15: 3841.Google Scholar
Schweityer, M. (1961). Ann. Med. N. Y. Acad. Sci., 91: 730–757.Google Scholar