Hostname: page-component-cd9895bd7-gvvz8 Total loading time: 0 Render date: 2024-12-25T01:05:28.105Z Has data issue: false hasContentIssue false
  • English
  • Français

Triple Mosaicism with Two Autosomally Unbalanced Cell Lines in a Phenotypically Normal Oligospermic Man

Published online by Cambridge University Press:  01 August 2014

Fiorella Shabtai ,
Shlomo Bichacho  and
Isaac Halbrecht
Fiorella Shabtai
Affiliation:
B. Gattegno Research Institute of Human Reproduction and Fetal Development, Department of Obstetrics and Gynecology, Hasharon Hospital, Petah-Tiqva, and, Tel-Aviv University Medical School, Israel
Shlomo Bichacho
Affiliation:
B. Gattegno Research Institute of Human Reproduction and Fetal Development, Department of Obstetrics and Gynecology, Hasharon Hospital, Petah-Tiqva, and, Tel-Aviv University Medical School, Israel
Isaac Halbrecht*
Affiliation:
B. Gattegno Research Institute of Human Reproduction and Fetal Development, Department of Obstetrics and Gynecology, Hasharon Hospital, Petah-Tiqva, and, Tel-Aviv University Medical School, Israel
*
B. Gattegno Research Institute of Human Reproduction and Fetal Development, Hasharon Hospital, Petah-Tiqva, Israel

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The chromosomal analysis of a phenotypically normal, moderately oligospermic man is reported. He presented a triple mosaic complement with two autosomally unbalanced cell lines. The cytogenetic results are discussed, and the importance of such investigations in men attending infertility clinics emphasized.

Type
Short Notes
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 26 , Issue 2 , April 1977 , pp. 177 - 180
Copyright
Copyright © The International Society for Twin Studies 1977

References

REFERENCES

Arrighi, F.E., Hsu, T.C. 1971. Localization of hetero-chromatin in human chromosomes. Cytogenetics, 10: 85.Google Scholar
Caspersson, T., Lindsten, J., Zech, L., Buckton, K., Price, W. 1972. Four patients with trisomy 8 identified by the fluorescence and Giemsa banding techniques. J. Med. Genet., 9:1.Google Scholar
Chandley, A.C., Edmond, P., Christie, S., Gowans, L., Fletcher, J., Frackiewicz, A., Newton, M. 1975. Cytogenetics and infertility in man. I. Karyotype and seminal analysis. Ann. Hum. Genet., 39: 231.Google Scholar
De Bault, L.E., Holmi, K.A. 1975. Familial trisomy 7 mosaicism. J. Med. Genet., 12: 200.Google Scholar
Ferguson-Smith, M.A., Handmaker, S.D. 1963. The association of satellited chromosomes with specific chromosomal regions in cultured human somatic cells. Ann. Hum. Genet., 27: 143.CrossRefGoogle ScholarPubMed
Hansmann, I. 1976. Structural variability of human chromosome 9 in relation to its evolution. Hum. Genet., 31: 247.Google Scholar
Hulten, M., Lindsten, J., Fraccaro, M., Mannini, A., Tiepolo, L. 1966. Extra minute chromosome in somatic and germ-line cells of the same person. Lancet, 2: 22.CrossRefGoogle ScholarPubMed
Kjessler, B. 1972. Facteurs génétiques dans la subfertilité mâle humaine. In: Thibault, Ch. (ed.): Fecondité et Stérilité du Mâle. Acquisitions Récentes (pp. 205–225). Paris: Masson et Cie.Google Scholar
Koulischer, L., Schoysman, R. 1974. Chromosomes and human infertility. I. Mitotic and meiotic chromosome studies in 202 consecutive male patients. Clin. Genet., 5: 116.Google Scholar
Millet, D., Plachot, M., Lety, M.A., De Grouchy, J., Netter, A. 1975. Les remaniements chromosomiques dans la stérilité masculine. J. Gynecol. Obstet. Biol. Reprod., 4: 689.Google Scholar
Moorhead, P.S., Nowell, P.C., Wellman, W.J., Battips, D.M., Hungerford, D.A. 1960. Chromosome preparations of leukocytes cultured from human peripheral blood. Exp. Cell Res., 20: 613.CrossRefGoogle ScholarPubMed
Seabright, M. 1971. A rapid banding technique for human chromosomes. Lancet, 2: 971.Google Scholar
Smith, K.D., Steimberger, E., Steimberger, A., Perloff, W. 1965. A familial centric chromosomic fragment. Cytogenetics, 4: 219.CrossRefGoogle ScholarPubMed
van Zyl, J.A., Menkveld, R., van W., Kotze, T.J., Retief, A.E., van Niekerk, W.A. 1975. Oligozoospermia. A seven-year survey of the incidence, chromosomal aberrations, treatment and pregnancy rate. Int. J. Fertil., 20: 129.Google ScholarPubMed
Ventruto, V., Coli, A., Farina, L., Festa, B., Ricciardi, L., Sebastio, L. 1976. A case of hypogonadotrophic hypogonadism with anosmia (Kallmann's syndrome) in a male, with familial incidence of a small metacentric chromosome (47, XY, mat ? +). J. Med. Genet., 13: 71.Google Scholar