This study estimates the effect of increases in age on 16 health problems that affect paid work for men and women in the United Kingdom. The analysis is based on a sample of the United Kingdom household population from the Office for National Statistics Labour Force Survey of 2007. Using multinomial logit regressions, the results reveal considerable diversity in the relationships between age and the reported prevalence of health problems that affect work. In particular, problems with heart, blood and circulation, arms and hands, legs and feet were strongly related to age, while difficulties in seeing and hearing, skin conditions and allergies appeared not to be more prevalent among older workers than younger employees. Regarding gender differences, it was found that, in general, women's health-related ability to participate in work was less affected by age, but that they suffered particular problems with arms and hands, skin conditions, allergies and depression. Finally, the study analyses the non-linear effects of unit increases in age. Such analysis may usefully identify the ages (or inflection points) at which ageing intensifies its effects on occupational health. These findings point to the importance of intervention at the appropriate time, when preventive measures may avoid the exacerbation of the health problem.