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Association of demographic, lifestyle factors and serum biomarkers with hypertension in elderly Chinese people

Published online by Cambridge University Press:  06 January 2016

XIUQIN HONG
Affiliation:
School of Public Health, Central South University, Changsha, China.
NUALNONG WONGTONGKAM*
Affiliation:
School of Biomedical Sciences, Charles Sturt University, Bathurst, NSW, Australia.
PAUL RUSSELL WARD
Affiliation:
School of Health Sciences, Faculty of Medicine, Nursing and Health Sciences, Flinders University, Adelaide, Australia.
SHUIYUAN XIAIO
Affiliation:
Center for Global Health, Central South University, Changsha, China.
SHULING WANG
Affiliation:
Institute of Gerontology, Hunan Geriatric Hospital, Changsha, China.
QIAN PENG
Affiliation:
Institute of Gerontology, Hunan Geriatric Hospital, Changsha, China.
QI ZUO
Affiliation:
Institute of Gerontology, Hunan Geriatric Hospital, Changsha, China.
DAN ZENG
Affiliation:
Institute of Gerontology, Hunan Geriatric Hospital, Changsha, China.
JIA WANG
Affiliation:
Institute of Gerontology, Hunan Geriatric Hospital, Changsha, China.
CHENXU WANG
Affiliation:
Institute of Gerontology, Hunan Geriatric Hospital, Changsha, China.
*
Address for correspondence: Nualnong Wongtongkam, School of Biomedical Sciences, Charles Sturt University, 1448-Building, Bathurst, NSW 2795, Australia E-mail: [email protected]

Abstract

Hypertension is a major cause of premature death in China. Understanding risk factors including behavioural and predisposing factors may help to prevent development of hypertension and control the extent of premature mortality. In this case-control design conducted in Hunan province, 416 hypertensive subjects were matched with an equal number of normotensive persons from nearly 9,000 volunteers. A self-report questionnaire was employed to collect demographic and lifestyle information, and fasting serum biomarkers related to lipid profile, renal function, glucose level and uric acid were assessed. When age and sex were stratified, serum biomarkers such as blood urea nitrogen and triglycerides showed a significant difference for hypertension, while lifestyle behaviours including university degree, alcohol use, Body Mass Index and psychological stress (job and married life) were also associated with hypertension. After adjusting for covariate confounding factors, only elevated triglyceride levels were strongly linked to high blood pressure, odds ratio = 1.55, 95 per cent confidence level = 1.16–2.06. To control high blood pressure, hypertriglyceridemia should be included in hypertension treatment and followed up to assess the substantial risk of cardiovascular diseases.

Type
Articles
Copyright
Copyright © Cambridge University Press 2016 

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