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Thyroid function and psychiatric disorders

Published online by Cambridge University Press:  18 September 2015

P.J.M. Schoof ,
L. Timmerman ,
E.J. Colon  and
H.J. Leijnse-Ybema
P.J.M. Schoof*
Affiliation:
Deltaziekenhuis, Poortugaal
L. Timmerman
Affiliation:
PAAZ Refaja ziekenhuis, Dordrecht
E.J. Colon
Affiliation:
Deltaziekenhuis, Poortugaal
H.J. Leijnse-Ybema
Affiliation:
hoofd Klinisch Chemisch Laboratorium, Deltaziekenhuis, Poortugaal
*
Deltaziekenhuis, Albrand-waardsedijk 74, 3172 AA Poortugaal
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Summary

To answer the question if it is possible for specific psychiatric illnesses to influence the thyroxine-concentration, a group of 376 patients admitted to a psychiatric hospital was studied retrospectively.

13.5% had an elevated thyroxine-concentration and only 0.6% had a low concentration.

Of the group of 145 men, 22.8% was found to have an elevated thyroxine-concentration. In the group of 196 women we found 6.6% to be elevated. A low thyroxine was found in only 0.5% of the women and 0.7% of the men.

In the group with an elevated thyroxine the psychiatric diagnoses of schizophrenia and psychotic disorders NOS are more common (19.6% and 17.4% respectively) than in the group with a normal thyroxine (4.4% and 6.5% respectively).

Keywords

psychiatric disordersthyroid functionthyroxine-concentrationschizophreniapsychotic disorders NOSpsychiatrische aandoeningenschildklierfunctieT4-concentratieschizofreniepsychotische aandoeningen NAO
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 3 , Issue 4 , December 1991 , pp. 61 - 64
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 1991

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