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The case for an Xq21.3/Yp homologous locus in the evolution of language and the origins of psychosis

Published online by Cambridge University Press:  18 September 2015

T.J. Crow
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Extract

The distribution of schizophrenia within populations bears upon the genetic nature of the disorder. From the World Health Organization Ten-Country Study of incidence Jablensky et al concluded that: Schizophrenic illnesses are ubiquitous, appear with similar incidence in different cultures and have clinical features that are more remarkable by their similarity across cultures than by their difference.

The WHO study included populations in Japan, India and Europe that have been separated for tens of thousands of years. Moreover illnesses with essentially the same characteristics are commonplace in the Australian aboriginal population that separated from other human populations 50,000 years ago.

Keywords

Brain symmetryhandednesslanguagelatéralisationpsychosis
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 11 , Issue 2 , June 1999 , pp. 54 - 56
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 1999

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References

Literature

2.Crow, TJ. Is schizophrenia the price that Homo sapiens pays for language? Schiz Res 1997;28;127–41.CrossRefGoogle ScholarPubMed
3.McGrew, WC, Marchant, LF. On the other hand: current issues in and meta-analysis of the behavioral laterality of hand function in nonhuman primates. Yearbook on Physical Anthropology 1997;40;201–32.3.0.CO;2-6>CrossRefGoogle Scholar
4.Buxhoeveden, D, Casanova, M. Comparative lateralization patterns in the language area of normal human, chimpanzee and rhesus monkey brain. Laterality (in press).Google Scholar
5.Annett, M. Left, Right, Hand and Brain: The Right Shift Theory. London, L. Erlbaum, 1985.Google Scholar
6.Crow, TJ. Nuclear schizophrenic symptoms as a window on the transition from thought to speech. Brit J Psychiat 1998;172;103–9.Google Scholar
7.Crow, TJ, Done, DJ, Sacker, A. Cerebral lateralization is delayed in children who later develop schizophrenia. Schizophr Res 1996;22;181–5.CrossRefGoogle ScholarPubMed
8.Crow, TJ, Crow, LR, Done, DJ, Leask, SJ. Relative hand skill predicts academic ability: global deficits at the point of hemispheric indecision. Neuropsychologia 1998;36;1275–82.CrossRefGoogle ScholarPubMed
9.Crow, TJ. Sexual selection, Machiavellian intelligence and the origins of psychosis. Lancet 1993;342;594–8.CrossRefGoogle ScholarPubMed
10.Corballis, MC, Lee, K, McManus, IC, Crow, TJ. The location of the handedness gene on the X and Y chromosomes. Am J med Genet (Neuropsychiatrie Genet) 1996;67;50–2.3.0.CO;2-W>CrossRefGoogle ScholarPubMed
11.Affara, NA, et al.Report of the second international workshop on Y chromosome mapping 1995. Cytogenet Cell Genet 1996;73;33–76.Google Scholar
12.Lambson, B, Affara, NA, Mitchell, M, Ferguson-Smith, MA. Evolution of DNA sequence homologies between the sex chromosomes in primate species. Genomics 1992;14;1032–40.CrossRefGoogle ScholarPubMed
13.Crow, TJ. Temporal lobe asymmetries as the key to the etiology of schizophrenia. Schizophr Bull 1990;16;433–43.CrossRefGoogle Scholar
14.Crow, TJ. Schizophrenia as failure of hemispheric dominance for language. Trends in Neurosci. 1997;20;339–43.Google ScholarPubMed
15.Highley, JR, Esiri, MM, Cortina-Borja, M, et al.Anomalies of asymmetry in schizophrenia interact with gender and age of onset: a post-mortem study. Schizophr Res 1998;34;13–25.CrossRefGoogle ScholarPubMed