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Published online by Cambridge University Press: 05 March 2022
In order to locate people’s ancestry to a region of the world through their DNA, the markers on their DNA sample have to be compared to population reference panels for the regions that form part of the comparison group. These ancestry inference methods have served medical research, forensic science, and commercial popular genealogical interests. According to Santo et al., the reliability of any ancestry inference depends on the existence of reliable population reference databases. Many researchers and ancestry DNA companies utilize different sources for population data on different countries. For example, ALFRED is an allele frequency database supported by the Yale Center for Medical Informatics, which has genomic data from population samples across the globe. You can enter the name of a country or population group, such as Siberian Yupik (the sample was collected from unrelated Siberian Yupiks from northeastern Siberia, Russia) and it will provide information on the number of people (29) and/or chromosomes sampled (58).
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