Book contents
- Uncommon Causes of Stroke
- Uncommon Causes of Stroke
- Copyright page
- Contents
- List of Contributors
- Preface
- PART I: INFECTIOUS AND INFLAMMATORY CONDITIONS
- PART II: HEREDITARY AND GENETIC CONDITIONS AND MALFORMATIONS
- PART III: VASCULAR CONDITIONS OF THE EYES, EARS, AND BRAIN
- 33 EALES RETINOPATHY
- 34 ACUTE POSTERIOR MULTIFOCAL PLACOID PIGMENT EPITHELIOPATHY
- 35 MICROANGIOPATHY OF THE RETINA, INNER EAR, AND BRAIN: SUSAC’S SYNDROME
- 36 HEREDITARY ENDOTHELIOPATHY WITH RETINOPATHY, NEPHROPATHY, AND STROKE (HERNS)
- 37 COGAN’S SYNDROME
- PART IV: DISORDERS INVOLVING ABNORMAL COAGULATION
- PART V: SYSTEMIC DISORDERS THAT ALSO INVOLVE THE CEREBROVASCULAR SYSTEM
- PART VI: NONINFLAMMATORY DISORDERS OF THE ARTERIAL WALL
- PART VII: VENOUS OCCLUSIVE CONDITIONS
- PART VIII: VASOSPASTIC CONDITIONS AND OTHER MISCELLANEOUS VASCULOPATHIES
- PART IX: OTHER MISCELLANEOUS CONDITIONS
- Index
34 - ACUTE POSTERIOR MULTIFOCAL PLACOID PIGMENT EPITHELIOPATHY
from PART III: - VASCULAR CONDITIONS OF THE EYES, EARS, AND BRAIN
Published online by Cambridge University Press: 06 January 2010
Book contents
- Uncommon Causes of Stroke
- Uncommon Causes of Stroke
- Copyright page
- Contents
- List of Contributors
- Preface
- PART I: INFECTIOUS AND INFLAMMATORY CONDITIONS
- PART II: HEREDITARY AND GENETIC CONDITIONS AND MALFORMATIONS
- PART III: VASCULAR CONDITIONS OF THE EYES, EARS, AND BRAIN
- 33 EALES RETINOPATHY
- 34 ACUTE POSTERIOR MULTIFOCAL PLACOID PIGMENT EPITHELIOPATHY
- 35 MICROANGIOPATHY OF THE RETINA, INNER EAR, AND BRAIN: SUSAC’S SYNDROME
- 36 HEREDITARY ENDOTHELIOPATHY WITH RETINOPATHY, NEPHROPATHY, AND STROKE (HERNS)
- 37 COGAN’S SYNDROME
- PART IV: DISORDERS INVOLVING ABNORMAL COAGULATION
- PART V: SYSTEMIC DISORDERS THAT ALSO INVOLVE THE CEREBROVASCULAR SYSTEM
- PART VI: NONINFLAMMATORY DISORDERS OF THE ARTERIAL WALL
- PART VII: VENOUS OCCLUSIVE CONDITIONS
- PART VIII: VASOSPASTIC CONDITIONS AND OTHER MISCELLANEOUS VASCULOPATHIES
- PART IX: OTHER MISCELLANEOUS CONDITIONS
- Index
Summary
Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is an ophthalmologic syndrome rather than a specific entity, characterized by multiple cream-colored placoid lesions located in the posterior pole "lying at the level of the pigment epithelium and choroids". The ophthalmoscopic hallmarks of APMPPE consist of creamcolored, flat, and discrete placoid, without clear-cut marginal lesions at the level of the retinal pigment epithelium, masking the fundus view of the underlying choroids, which typically involve the macula but are never seen anterior to the equator. The fact that cardiovascular diseases (CVDs) occur in patients with APMPPE strongly supports the thesis that it represents a particular "uveo-cerebral vasculitic syndrome". Various etiologies have been found (infectious/postinfectious; vaccinations; inflammations; autoimmune diseases; vasculitis; paraneoplastic syndrome). The neurological complications of APMPPE are headache, aseptic meningitis, encephalitis, multiple sclerosis-like disease, and pseudo tumor cerebri. CVDs associated with APMPPE consist of ischemic cortical strokes and deep infarcts with striatocapsular infarctions.
Keywords
- Type
- Chapter
- Information
- Uncommon Causes of Stroke , pp. 237 - 246Publisher: Cambridge University PressPrint publication year: 2008
- 2
- Cited by