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  1. Home
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  3. Treatment-Resistant Mood Disorders
  • Cited by 8
Publisher:
Cambridge University Press
Online publication date:
March 2010
Print publication year:
2001
Online ISBN:
9780511666421
DOI:
https://doi.org/10.1017/CBO9780511666421
Subjects:
Psychiatry and Clinical Psychology, Medicine, Psychiatry
Information

Book description

While antidepressants have helped millions worldwide, a substantial proportion of patients fail to respond or remit. There is little published information available to clinicians for diagnosis and management of treatment-resistant depression, so they have had to make difficult decisions about treatment options with very limited data. The editors and their internationally distinguished team of contributors have set out to address this problem, giving a critical assessment of all aspects of treatment-resistant depression: causes, epidemiology, comorbidity, evaluation and treatment. This timely book will be invaluable to clinicians, neuroscientists, researchers and graduate students.

Reviews

‘The excellence of this book is the section on special patient populations. They are all extremely well covered … This book will be valuable for researchers, academics who are interested in the scholarly reviews and algorithms of treatments, clinicians with special interest in affective disorders, and any clinician who would like a valuable resource book in their library.’

Source: International Journal of Geriatric Psychiatry

'The book is strong on the psychological aspects and it is pleasing to note that dysthymia - a difficult concept in relation to these disorders - is sensibly handled, as this has often caused confusion in the US/UK literature.'

Source: British Journal of Psychiatry

'It is a good description of current thinking and a useful book to have for reference text.'

Source: Journal of Psychosomatic Research

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Contents

Page 2 of 2

Contents
  • 22 - Ethical issues in research and treatment of patients with mood disorders
    pp 504-516
  • View abstract

    Summary

    Patients with mood disorders pose ethical challenges for both the clinicians who treat them and the researchers who study them. Depressed patients are often indecisive or resistant to treatment, which raises the dilemma of when to consider such resistance a reasonable refusal of consent and when the resistance is a product of the illness itself. Mood disorders, like many psychiatric illnesses, often provoke a variety of crises in the lives of patients, from loss of relationships and employment to self-destructive behavior and suicidality. The ethical problems most common to mood-disordered patients revolve around the difficult issues of capacity and informed consent. Among patients with mood disorders, there are cases where decision-making capacity is impaired to the point at which others must take over the decision-making role for the patient. The ethical problems with the schizophrenia washout studies are equally applicable to subjects with mood disorders.

Page 2 of 2

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