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Case 16 - A 45-Year-Old Female with Multifocal VIN

Published online by Cambridge University Press:  19 November 2021

By
Esther Fuchs
Edited by
Todd R. Jenkins ,
Lisa Keder ,
Abimola Famuyide ,
Kimberly S. Gecsi  and
David Chelmow
Todd R. Jenkins
Affiliation:
University of Alabama, Birmingham
Lisa Keder
Affiliation:
Ohio State University School of Medicine, Columbus
Abimola Famuyide
Affiliation:
Mayo Clinic, Rochester
Kimberly S. Gecsi
Affiliation:
Medical College of Wisconsin
David Chelmow
Affiliation:
Virginia Commonwealth University School of Medicine
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Summary

A 45-year-old female presents to the office with itching in the vulvar area. The symptoms have been present for several weeks and are progressively getting worse. She recently felt some skin thickening between the vaginal introitus and anus. Her history is remarkable for genital warts that resolved after cryotherapy 10 years ago. Additionally, she had a loop electrosurgical excision procedure (LEEP) procedure six years ago for severe cervical dysplasia but has had normal cervical cytology on follow-up.

Keywords

vulvar intraepithelial neoplasiaVINlaser ablation
Type
Chapter
Information
Surgical Gynecology
A Case-Based Approach
 , pp. 42 - 44
Publisher: Cambridge University Press
Print publication year: 2021

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References

Van Seters, M, van Beurden, M, de Craen, AJ. Is the assumed natural history of vulvar intraepithelial neoplasia III based on enough evidence? A systematic review of 3322 published patients. Gynecol Oncol 2005; 97: 645–51.CrossRefGoogle ScholarPubMed
Bornstein, J, Bogliatto, F, Haefner, HK, et al. The 2015 International Society for the Study of Vulvovaginal Disease (ISSVD) Terminology of Vulvar Squamous Intraepithelial Lesions. Obstet Gynecol 2016; 127: 264–8.CrossRefGoogle Scholar
Committee Opinion No.675: Management of vulvar intraepithelial neoplasia. Obstet Gynecol. 2016; 128: e178–82. Erratum in: Obstet Gynecol 2017; 129: 209.Google Scholar
DeLeon, F, Baggish, M. Lasers in gynecology. Glob Libr Women’s Med 2008. (ISSN: 1756-2228); doi 10.3843/GLOWM.10023.CrossRefGoogle Scholar
Pepas, L, Kaushik, S, Nordin, A, Bryant, A, Lawrie, TA. Medical interventions for high‐grade vulval intraepithelial neoplasia. Cochrane Database Syst Rev 2015; 2015(8): CD007924.Google ScholarPubMed
Jones, RW, Rowan, DM, Stewart, AW. Vulvar intraepithelial neoplasia: aspects of the natural history and outcome in 405 women. Obstet Gynecol 2005; 106: 1319–26.CrossRefGoogle ScholarPubMed
Wallbillich, JJ, Rhodes, HE, Milbourne, AM, et al. Vulvar intraepithelial neoplasia (VIN 2/3): comparing clinical outcomes and evaluating risk factors for recurrence. Gynecol Oncol 2012; 127: 312–15.CrossRefGoogle ScholarPubMed
Satmary, W, Holschneider, CH, Brunette, LL, Natarajan, S. Vulvar intraepithelial neoplasia: risk factors for recurrence. Gynecol Oncol 2018; 148: 126–31.CrossRefGoogle ScholarPubMed

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