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Chapter 4 - Pharmacodynamics and Pharmacokinetics

from Part 1 - Basic Science and General Principles

Published online by Cambridge University Press:  29 May 2020

By
Stuart Banham  and
David Taylor
Edited by
Peter M. Haddad  and
David J. Nutt
Peter M. Haddad
Affiliation:
Hamad Medical Corporation, Qatar
David J. Nutt
Affiliation:
Centre for Neuropsychopharmacology, Division of Psychiatry, Department of Brain Sciences, Imperial College London
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Summary

Pharmacokinetics refers to the effects the body has upon a consumed drug, by considering a variety of processes which a dug undergoes during its time within the body. In contrast pharmacodynamics can be considered as the effects a drug has upon the body that has consumed it, by considering the drug’s effects at its principal sites of action. Safe and effective therapeutic management of drugs for individual patients requires application of pharmacokinetic and pharmacodynamic principles to enhance efficacy and minimize toxicity. Chapter 5 (Pharmacogenomics and Psychopharmacology) provides a detailed review of the genes relevant for drug absorption, distribution, metabolism and excretion. As such these issues are only dealt with briefly in this chapter.

Type
Chapter
Information
Seminars in Clinical Psychopharmacology , pp. 124 - 150
Publisher: Cambridge University Press
Print publication year: 2020

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