from Section III - Care of the Elderly by Organ System
Published online by Cambridge University Press: 30 June 2022
Aging leads to progressive deterioration of physiological function and predisposes to pathological processes. Common geriatric syndromes (such as depression, dementia, falls, mobility impairment, delirium, and osteoporosis), along with age-related impairment in appetite, absorption, and food intake, affect nutrition, symptom presentation, and response to therapy of common gastrointestinal (GI) disorders in the elderly. Age-associated changes in drug metabolism and polypharmacy can result in potential interactions and side effects of drugs used in the treatment of GI diseases, which in turn complicates their management. Polypharmacy, which is common in the elderly, can also exacerbate digestive symptoms. Elderly patients with neurocognitive decline often have atypical presentation of their GI disorders. These factors can make the diagnosis of GI diseases in the elderly more challenging, as they may require different management approaches. In this chapter, we discuss the common GI disorders that affect the elderly with special focus on age-related pathophysiology and clinical implications.
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