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Chapter 13 - Set-Up Procedures for Optimizing Performance in the IVF Laboratory

from Section 2 - Pre-procedure Protocols

Published online by Cambridge University Press:  07 August 2023

Markus H. M. Montag
Affiliation:
ilabcomm GmbH, St Augustin, Germany
Dean E. Morbeck
Affiliation:
Kindbody Inc, New York City
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Summary

Optimization of procedures routinely performed in a clinical human in vitro fertilization (IVF) laboratory have become increasingly important due to the increase in complexity of procedures now performed in the laboratory. The addition of new technologies requiring more oversight has increased dramatically within the last decade. As a result of incorporating these new technologies, safe and efficient operation of the IVF laboratory has become increasingly complex and requires a substantial understanding of processes within the laboratory. In today’s modern IVF laboratory, the amount of staff time to perform every increasingly complicated case has more than doubled. Similarly, the amount required time to prepare for these cases has increased dramatically as well. In many instances, the increase in complexity of laboratory procedures has not translated into hiring of new staff but the creation of challenges to improve efficiency within the laboratory. The current guidelines for allocation of staff are based upon cycle numbers performed on an annual basis, not complexity of cases performed.

Type
Chapter
Information
Principles of IVF Laboratory Practice
Laboratory Set-Up, Training and Daily Operation
, pp. 96 - 104
Publisher: Cambridge University Press
Print publication year: 2023

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References

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Practice Committee of the American Society for Reproductive Medicine. Revised guidelines for human embryology and andrology laboratories. Fertil Steril 2008; 90(Suppl. 3):S45–59.Google Scholar
Lundin, K. and Ahlström, A. Quality control and standardization of embryo morphology scoring and viability marker. Reprod Biomed Online 2015; 31(4):459–71.CrossRefGoogle Scholar
Hughes, M. P., Morbeck, D. E., Hudson, S. B. A., et al. Peroxides in mineral oil used for in vitro fertilization: defining limits of standards quality control assays. J Assist Reprod. Genet 2010; 27:8792.CrossRefGoogle ScholarPubMed
Morbeck, D. E., Khan, Z., Barnidge, D. R. and Walker, D. Washing mineral reduces contaminants and embryotoxicity. Fertil Steril 2010; 94:2747–52.CrossRefGoogle ScholarPubMed

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