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Case 37 - A 25-Year-Old with Elevated Hemoglobin A2 on Initial Prenatal Labs

from Section 4 - Antepartum (Medical Complications)

Published online by Cambridge University Press:  08 April 2025

Peter F. Schnatz
Affiliation:
The Reading Hospital, Pennsylvania
D. Yvette LaCoursiere
Affiliation:
University of California, San Diego
Christopher M. Morosky
Affiliation:
University of Connecticut School of Medicine
Jonathan Schaffir
Affiliation:
The Ohio State University College of Medicine
Vanessa Torbenson
Affiliation:
Mayo Clinic Alix School of Medicine
David Chelmow
Affiliation:
Virginia Commonwealth School of Medicine
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Summary

Hemoglobinopathies are vast grouping of inherited disorders of the hemoglobin chain genes that affect over 270 million people globally. The most common hemoglobinopathies include sickle cell, alpha- thalassemia, and beta-thalassemia. Each of these diseases has numerous phenotypes and thus presentation and management of each will vary. Generally, the carrier or asymptomatic states have pregnancy outcomes that mirror the general population. Patients with clinically significant disease are at increased risk for numerous maternal and fetal complications. All patients desiring pregnancy and those that are currently pregnant should be screened for hemoglobinopathy and those found to have one provided with genetic counseling regarding any potential maternal or fetal risks.

Type
Chapter
Information
Pregnancy Complications
A Case-Based Approach
, pp. 112 - 114
Publisher: Cambridge University Press
Print publication year: 2025

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References

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