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22 - Acute Respiratory Distress Syndrome

from Section 5 - Respiratory Emergencies

Published online by Cambridge University Press:  02 November 2023

Kaushal Shah
Affiliation:
Weill Cornell Medical Center, New York
Jarone Lee
Affiliation:
Massachusetts General Hospital, Boston
Clark G. Owyang
Affiliation:
Weill Cornell Medical Center, New York
Benjamin Christian Renne
Affiliation:
Massachusetts General Hospital, Boston
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Summary

Acute respiratory distress syndrome (ARDS) is severe respiratory distress of an acute and persistent nature, caused by one or more predisposing conditions and resulting in refractory arterial hypoxemia. The pathophysiology of ARDS is characterized by fluid buildup within alveoli, causing surfactant dysfunction and decreased lung compliance. Approximately 50% of cases are due to severe infection, either focal (such as pneumonia) or systemic (such as sepsis).

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Publisher: Cambridge University Press
Print publication year: 2023

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References

Ranieri, VM, Rubenfeld, GD, Thompson, BT, et al. Acute respiratory distress syndrome: The Berlin Definition. JAMA 2012;307:25262533.Google ScholarPubMed

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