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Chapter 47 - Hyperleukocytosis and Leukostasis

from Section 5 - Lymphatic System

Published online by Cambridge University Press:  10 August 2023

Monica Kathleen Wattana
Monica Kathleen Wattana
Affiliation:
University of Texas, MD Anderson Cancer Center
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Summary

Overview of toxicities related to immunotherapy agents, and other complications in the lymphatic system such as tumor lysis, hyperviscosity syndrome, graft vs host disease, and neutropenic fever

Keywords

tumor lysisacute leukemianeutropenic feverdifferentiation syndrome
Type
Chapter
Information
Pocket Guide to Oncologic Emergencies , pp. 195 - 198
Publisher: Cambridge University Press
Print publication year: 2023

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References

Bewersdorf, JP, Zeidan, AM. Hyperleukocytosis and leukostasis in acute myeloid leukemia: Can a better understanding of the underlying molecular pathophysiology lead to novel treatments? Cells. 2020;9(10):2310. Doi: 10.3390/cells9102310.CrossRefGoogle ScholarPubMed
Ghosh, K, Malik, K, Das, KC. Serum and leukocyte lactate dehydrogenase activity in leukaemias. Haematologia. 1988;21(4) :227–232.Google ScholarPubMed
Macaron, W, Sargsyan, Z, Short, NJ. Hyperleukocytosis and leukostasis in acute and chronic leukemias. Leukemia & Lymphoma. 2022;63(8). Doi: 10.1080/10428194.2022.2056178.CrossRefGoogle ScholarPubMed
Stefanski, M, Jamis-Dow, C, Bayerl, M, Desai, RJ, Claxton, DF, Van de Louw, A. Chest radiographic and CT findings in hyperleukocytic acute myeloid leukemia: A retrospective cohort study of 73 patients. Medicine. 2016;95(44):e5285. Doi: 10.1097/MD.0000000000005285.CrossRefGoogle ScholarPubMed

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