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Chapter 20 - Assisted reproductive technology and the risk of poor pregnancy outcome

from Section 7: - Risk factors, predictors, and future management

Published online by Cambridge University Press:  06 July 2010

Robert Pijnenborg
Affiliation:
University Hospital Gasthuisberg, Leuven
Ivo Brosens
Affiliation:
Leuven Institute for Fertility and Embryology
Roberto Romero
Affiliation:
National Institute of Child Health and Human Development, Detroit
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Summary

This chapter deals with perinatal outcomes, i.e. outcomes of pregnancies that have surpassed the early hurdles and have evolved far enough to result in a birth, internationally defined as the separation from its mother of a fetus weighing 500 g or more. Assisted reproductive technology (ART) involves a whole gamut of interventions, used either as a single intervention or in combination, to address alleged dysfunction of one or more of the four crucial elements needed to achieve a successful pregnancy. A large number of studies of pregnancy outcome after ART provide data on small for gestational age (SGA), usually defined as a birth weight below the 10th centile of weight for gestation. The first indication that the perinatal outcome of singleton pregnancies is worse after ART than after natural conception dates back nearly 25 years.
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Chapter
Information
Placental Bed Disorders
Basic Science and its Translation to Obstetrics
, pp. 207 - 228
Publisher: Cambridge University Press
Print publication year: 2010

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