Book contents
- The Placenta and Human Developmental Programming
- The Placenta and Human Developmental Programming
- Copyright page
- Contents
- Contributors
- Preface
- 1 Introduction
- 2 The maternal and placental origins of chronic disease
- 3 Pre- and periconceptual health and the HPA axis
- 4 Nutrition and preimplantation development
- 5 Maternofetal transport pathways during embryogenesis and organogenesis
- 6 Imprinted genes and placental growth
- 7 Genomic imprinting
- 8 Trophoblast invasion and uterine artery remodelling in primates
- 9 The role of the maternal immune response in fetal programming
- 10 Clinical causes and aspects of placental insufficiency
- 11 Uterine blood flow as a determinant of fetoplacental development
- 12 Placental amino acid transporters
- 13 The maternal circulation and placental shape
- 14 Glucocorticoids and placental programming
- 15 Clinical biomarkers of placental development
- 16 The placental roots of cardiovascular disease
- 17 Placental function and later risk of osteoporosis
- 18 Final general discussion
- 19 The placenta and developmental programming
- Index
1 - Introduction
Published online by Cambridge University Press: 04 February 2011
Book contents
- The Placenta and Human Developmental Programming
- The Placenta and Human Developmental Programming
- Copyright page
- Contents
- Contributors
- Preface
- 1 Introduction
- 2 The maternal and placental origins of chronic disease
- 3 Pre- and periconceptual health and the HPA axis
- 4 Nutrition and preimplantation development
- 5 Maternofetal transport pathways during embryogenesis and organogenesis
- 6 Imprinted genes and placental growth
- 7 Genomic imprinting
- 8 Trophoblast invasion and uterine artery remodelling in primates
- 9 The role of the maternal immune response in fetal programming
- 10 Clinical causes and aspects of placental insufficiency
- 11 Uterine blood flow as a determinant of fetoplacental development
- 12 Placental amino acid transporters
- 13 The maternal circulation and placental shape
- 14 Glucocorticoids and placental programming
- 15 Clinical biomarkers of placental development
- 16 The placental roots of cardiovascular disease
- 17 Placental function and later risk of osteoporosis
- 18 Final general discussion
- 19 The placenta and developmental programming
- Index
Summary
This introduction provides an overview of the concepts discussed in the book The Placenta and Human Developmental Programming. Developmental programming of the fetus is a phenomenon that has profound implications for the health of individuals and societies. This book explores the current knowledge of the ways in which various aspects of placental development and function may influence fetal programming, and aims to promote further scientific research in their respective fields. The development of the placenta is not autonomous, but is clearly heavily influenced by the uterine mucosa with which the trophoblast interacts. Assessment of placental function in vivo is obviously important for clinical diagnosis and monitoring. The capacity of the placenta to supply adequate nutrients to the fetus is obviously of central importance to the role of the organ in developmental programming, but other aspects of placental function may also operate.
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- Information
- The Placenta and Human Developmental Programming , pp. 1 - 4Publisher: Cambridge University PressPrint publication year: 2010
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