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64 - Renal failure and transplantation

from Part VII - Transplantation

Published online by Cambridge University Press:  08 January 2010

By
Maria H. Alonso ,
Greg Tiao  and
Frederick C. Ryckman
Edited by
Mark D. Stringer ,
Keith T. Oldham  and
Pierre D. E. Mouriquand
Maria H. Alonso
Affiliation:
Department of Pediatric General and Thoracic Surgery, Transplantation Division, Cincinnati Children's Hospital Medical Center, OH, USA
Greg Tiao
Affiliation:
Department of Pediatric General and Thoracic Surgery, Transplantation Division, Cincinnati Children's Hospital Medical Center, OH, USA
Frederick C. Ryckman
Affiliation:
Department of Pediatric General and Thoracic Surgery, Transplantation Division, Cincinnati Children's Hospital Medical Center, OH, USA
Mark D. Stringer
Affiliation:
University of Otago, New Zealand
Keith T. Oldham
Affiliation:
Children's Hospital of Wisconsin
Pierre D. E. Mouriquand
Affiliation:
Debrousse Hospital, Lyon
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Summary

Introduction

The management of end-stage renal disease, encompassing the principles of medical management, dialysis, and renal transplantation, formed the early experience with organ failure and replacement. The lessons learned were the basis for the exploding growth of solid organ replacement in children and adults. The care continuum for these patients can be divided into several phases: pretransplant medical management, transplantation, short- and long-term outcome. In this chapter, we will attempt to review the factors affecting success in medical pretransplant management, the transplant procedure, and throughout the short- and long-term follow-up periods. At each stage of care, factors which can determine the likelihood of success may be assigned (age, sex, ethnicity, primary disease, etc.). Some determinants of outcome are variable, that is, they are influenced by choices in care delivery (type of transplant, immunosuppression protocol, experience of transplant center, etc.). As the phases of transplantation are reviewed, we will attempt to identify avenues to improve outcome based on the application of current data.

Information reviewing the management of children with end-stage renal disease has been regularly evaluated and compiled in several large registries, allowing analysis of large cohorts. The United Network for Organ Sharing (UNOS)(www.unos.org) collects information on renal replacement in the United States, the United States Renal Data Systems (www.usrds.org) collects information regarding transplantation in Medicare patients.

Type
Chapter
Information
Pediatric Surgery and Urology
Long-Term Outcomes
 , pp. 845 - 857
Publisher: Cambridge University Press
Print publication year: 2006

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References

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  • Renal failure and transplantation
    • By Maria H. Alonso, Department of Pediatric General and Thoracic Surgery, Transplantation Division, Cincinnati Children's Hospital Medical Center, OH, USA, Greg Tiao, Department of Pediatric General and Thoracic Surgery, Transplantation Division, Cincinnati Children's Hospital Medical Center, OH, USA, Frederick C. Ryckman, Department of Pediatric General and Thoracic Surgery, Transplantation Division, Cincinnati Children's Hospital Medical Center, OH, USA
  • Edited by Mark D. Stringer, Keith T. Oldham, Pierre D. E. Mouriquand
  • Book: Pediatric Surgery and Urology
  • Online publication: 08 January 2010
  • Chapter DOI: https://doi.org/10.1017/CBO9780511545757.065
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Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

  • Renal failure and transplantation
    • By Maria H. Alonso, Department of Pediatric General and Thoracic Surgery, Transplantation Division, Cincinnati Children's Hospital Medical Center, OH, USA, Greg Tiao, Department of Pediatric General and Thoracic Surgery, Transplantation Division, Cincinnati Children's Hospital Medical Center, OH, USA, Frederick C. Ryckman, Department of Pediatric General and Thoracic Surgery, Transplantation Division, Cincinnati Children's Hospital Medical Center, OH, USA
  • Edited by Mark D. Stringer, Keith T. Oldham, Pierre D. E. Mouriquand
  • Book: Pediatric Surgery and Urology
  • Online publication: 08 January 2010
  • Chapter DOI: https://doi.org/10.1017/CBO9780511545757.065
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Renal failure and transplantation
    • By Maria H. Alonso, Department of Pediatric General and Thoracic Surgery, Transplantation Division, Cincinnati Children's Hospital Medical Center, OH, USA, Greg Tiao, Department of Pediatric General and Thoracic Surgery, Transplantation Division, Cincinnati Children's Hospital Medical Center, OH, USA, Frederick C. Ryckman, Department of Pediatric General and Thoracic Surgery, Transplantation Division, Cincinnati Children's Hospital Medical Center, OH, USA
  • Edited by Mark D. Stringer, Keith T. Oldham, Pierre D. E. Mouriquand
  • Book: Pediatric Surgery and Urology
  • Online publication: 08 January 2010
  • Chapter DOI: https://doi.org/10.1017/CBO9780511545757.065
Available formats
×