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Chapter 30 - Schizophrenia in Pregnancy

from Section 5 - Psychiatric Disorders in Pregnancy

Published online by Cambridge University Press:  23 February 2023

Amira El-Messidi
Affiliation:
McGill University, Montréal
Alan D. Cameron
Affiliation:
University of Glasgow
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Summary

A 30-year-old primigravida with schizophrenia is referred by her primary care provider to your high-risk obstetrics unit at a tertiary center. Her mental illness is controlled by clozapine, and she takes routine prenatal vitamins. The patient is at 12+2 weeks’ gestation by dating sonography; first-trimester fetal anatomy was normal with a low risk of aneuploidy. Results of routine prenatal investigations are unremarkable. The patient does not have any obstetric complaints.

Type
Chapter
Information
OSCEs in Obstetrics and Maternal-Fetal Medicine
An Evidence-Based Approach
, pp. 397 - 406
Publisher: Cambridge University Press
Print publication year: 2023

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References

Suggested Readings

ACOG Committee on Practice Bulletins – Obstetrics. ACOG Practice Bulletin: Clinical management guidelines for obstetrician-gynecologists No. 92. Use of psychiatric medications during pregnancy and lactation. Obstet Gynecol. 2008;111(4):10011020.Google Scholar
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Jones, I, Chandra, PS, Dazzan, P, et al. Bipolar disorder, affective psychosis, and schizophrenia in pregnancy and the post-partum period. The Lancet. 2014 Nov 15;384(9956):17891799.Google Scholar
Poo, SX, Agius, M. Atypical antipsychotics for schizophrenia and/or bipolar disorder in pregnancy: current recommendations and updates in the NICE guidelines. Psychiatr Danub. 2015;27(Suppl 1):S255S260.Google Scholar
Rasic, D, Hajek, T, Alda, M, et al. Risk of mental illness in offspring of parents with schizophrenia, bipolar disorder, and major depressive disorder: a meta-analysis of family high-risk studies. Schizophr Bull. 2014;40(1):2838.CrossRefGoogle ScholarPubMed
Robinson, GE. Treatment of schizophrenia in pregnancy and postpartum. J Popul Ther Clin Pharmacol. 2012;19(3):e380e386.Google Scholar

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