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Chapter 26 - Autoimmune Disease

Published online by Cambridge University Press:  26 January 2024

David R. Gambling
Affiliation:
University of California, San Diego
M. Joanne Douglas
Affiliation:
University of British Columbia, Vancouver
Grace Lim
Affiliation:
University of Pittsburgh
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Summary

An autoimmune disease represents a pathological condition caused by an immune response directed against an antigen within the body of the host. The incidence and activity of autoimmune diseases are particularly high in young women and hence their occurrence in parturients is not uncommon. Autoimmune diseases often involve multiple systems and have a wide range of clinical manifestations and complications necessitating a multidisciplinary approach to management in the obstetric population, involving obstetricians, anesthesiologists, neonatologists, and rheumatologists. All affected organ systems should be evaluated and advice from appropriate medical specialties sought. The effect of autoimmune diseases and their treatment on pregnancy, and the effect of pregnancy on the disease itself varies between individual diseases. This chapter discusses the implications of the following autoimmune diseases in pregnancy: rheumatoid arthritis, systemic lupus erythematosus, polyarteritis nodosa, systemic sclerosis, antiphospholipid syndrome, and multiple sclerosis.

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Publisher: Cambridge University Press
Print publication year: 2024

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Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

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Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

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Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

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