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Published online by Cambridge University Press: 05 August 2012
The isolated soy-based formulas on the USA market are free of cow's milk protein and lactose. The soy protein is a soy isolate supplemented with L-methionine, L-carnitine and taurine. Soy-based formulas are not designed to meet the nutritional needs of the premature infant. These are not recommended because of the low calcium and phosphorus content of these formulas as well as generally not meeting the nutritional requirements for VLBW infants. Preterm infants fed soy protein formulas have significantly lower serum phosphorus and serum alkaline phosphatase levels and an increased risk of development of osteopenia. Even when supplemented with additional calcium, phosphorus, and vitamin D, VLBW infants fed these formulas exhibit slower weight gain and lower serum protein and albumin concentrations than infants receiving a whey-predominant premature infant formula.
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